fatigability

Abstract Chronic muscle fatigue is a condition characterized by debilitating muscle weakness and pain. Based on our recent finding to study the potential effect of mTOR on ATG13 inactivation in chronic muscle fatigue, we report that biweekly oral administration with MHY1485, a potent inducer of...

From @MSEsperanza: Prominent Fatigue but No Motor Fatigability in Non-Hospitalized Patients With Post-COVID-Syndrome Abstract Objectives: Fatigue is a frequent and often disabling symptom in patients with post-COVID syndrome. To better understand and evaluate the symptom of motor fatigue in...

Effect of the subjective intensity of fatigue and interoception on perceptual regulation and performance during sustained physical activity Aaron Greenhouse-Tucknott , Jake B. Butterworth, James G. Wrightson, Neil A. Harrison, Jeanne Dekerle Abstract Background The subjective experience of...

[I think this is the right forum for this study but please move if it's in the wrong place] Cerebellar Excitability Regulates Physical Fatigue Perception https://www.jneurosci.org/content/43/17/3094 The Washington Post has an article discussing this study which is how I found it: Rethinking...

Fatigue is a major symptom in many diseases, often among the most common and severe ones and may last for an extremely long period. Chronic fatigue impacts quality of life, reduces the capacity to perform activities of daily living, and has socioeconomical consequences such as impairing return...

Abstract Persistent symptoms after acute COVID-19 infection, termed post-COVID-19 fatigue, occur in 44–70% of patients. Characterizing fatigue in this population is vital to determine the etiology of post-COVID-19 fatigue symptoms and to assess the effectiveness of potential interventions...

Abstract The acute phase of COVID-19 has been well studied, however with increasing post-acute COVID-19 syndrome, much is unknown about its long-term effects. A common symptom in both the acute and post-acute phases has been fatigue, assessed predominantly qualitatively. Here we present a...

“What we’re trying to do is generate a unique ME/CFS signature based on characteristic changes to eye movements, a behaviourial signature that is specific to the disorder that can be used to help diagnose it and monitor the effects of any treatments.” “Tentatively, what we’ve found already...

My muscle strength declines rapidly after a certain time walking and then takes a while to come back. It also likes to decline shortly after stopping the activity (usually walking), as if the body was waiting for an opportunity to start resting. The recovery time seems unusually long. I also...

Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex and debilitating disease accompanied by muscular fatigue and pain. A functional measure to assess muscle fatigability of ME/CFS patients is, however, not established in clinical routine. The aim of this...

Just in case you thought we were the only ones having to put up with this crap: The middle bit sounds promising to me. The rest is the usual BS. Although it doesn't explicitly mention negative illness beliefs, I think that's implicit in the suggestion of CBT. I love how they think the fatigue...

Threads have been merged Fatigue as presence of sensation or absence? This is another one of those posts where I try to describe some highly subjective symptom in the hopes of improving our understanding of the illness. I think that everyone knows the kind of fatigue where there is an intense...

The following list of studies and other papers could be helpful with regard to the claim that symptoms classified as 'fatigue' can't be measured objectively, or that potential objective measures are too unspecific. In the field of MS research, some people looked for objective measures...