Sympathetic Neural Overdrive, Vascular Dysfunction and Diminished Exercise Capacity in Long COVID-19 Patients: A Long-Term Study of Cardiovascular Sequelae
Bruna E. Ono; João E. Izaias; Artur O. Sales; Thais S. Rodrigues; Camila S. Nunes; Jessica F. Niec; Natalia G. Rocha; Helena N.M. Rocha...
Regulation of synaptic mitochondria by extracellular vesicles and its implications for neuronal metabolism and synaptic plasticity
Yuzhou Zeng; Anna Antoniou
Mitochondrial metabolism in neurons is necessary for energetically costly processes like synaptic transmission and plasticity. As...
MicroRNA Profiling of Blood Extracellular Vesicles in ME/CFS
Ljungström, María; Nathanson, Lubov; Oltra, Elisa
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitating neuroimmune disease affecting many organs and systems which, in the absence of validated...
SARS-CoV-2 post-acute sequelae linked to inflammation via extracellular vesicles
Sara Bachiller, Joana Vitalle, Lluís Camprubí-Ferrer, Manuel García, Isabel Gallego, Marina López-García, María Isabel Galvá, Julio Cañizares, Inmaculada Rivas-Jeremías, María Díaz-Mateos, Carmen Gasca-Capote...
Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response
Arpita Balakrishnan, Gabriela Winiarek, Olga Ho, Jakub Godlewski, Agnieszka Bronisz
Abstract
The immunopeptidome, a diverse set of peptides presented by Major Histocompatibility...
Surface Protein Profiling of Extracellular Vesicles: A Novel Biomarker Approach for Long COVID Diagnosis?
Gentaro Ikeda, Prasanna Jagannathan, Mario Leki, Hiroyuki Inoue, Vanessa El Kamari, Arya V Dadhania, Mitchell Miglis, Robert W Shafer, Linda N Geng, Phillip C Yang, Hector F Bonilla...
Platelets as key cells in endometriosis patients: Insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis
Barbara Bortot; Roberta Di Florio; Simona Merighi; Ben Peacock; Rebecca Lees; Francesco Valle; Marco Brucale; Alessandro Mangogna; Giovanni Di...
Flow cytometry for extracellular vesicle characterization in COVID-19 and post-acute sequelae of SARS-CoV-2 infection
Marialaura Fanelli; Vita Petrone; Rossella Chirico; Claudia Maria Radu; Antonella Minutolo; Claudia Matteucci
Infection with SARS-CoV-2, the virus responsible for COVID-19...
Astrocytic mitochondrial transfer to brain endothelial cells and pericytes in vivo increases with aging
Gopal V Velmurugan; Hemendra J Vekaria; Samir P Patel; Patrick G Sullivan; W Brad Hubbard
Intercellular mitochondrial transfer (IMT) is an intriguing biological phenomenon where mitochondria...
miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses
Paola Pinto-Hernandez; Manuel Fernandez-Sanjurjo; Daan Paget; Xurde M Caravia; David Roiz-Valle; Juan Castilla-Silgado; Sergio Diez-Robles; Almudena Coto-Vilcapoma; Pau Gama; Pablo M Garcia-Roves...
Microfluidic Isolation of Neuronal-Enriched Extracellular Vesicles Shows Distinct and Common Neurological Proteins in Long COVID, HIV Infection and Alzheimer’s Disease
Pulliam, Lynn; Sun, Bing; McCafferty, Erin; Soper, Steven A.; Witek, Malgorzata A.; Hu, Mengjia; Ford, Judith M.; Song, Sarah...
Blood Markers Show Neural Consequences of LongCOVID-19
Tang, Norina; Kido, Tatsuo; Shi, Jian; McCafferty, Erin; Ford, Judith M.; Dal Bon, Kaitlyn; Pulliam, Lynn
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persists throughout the world with over 65 million registered cases of...
Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
Todkar, Kiran; Chikhi, Lilia; Desjardins, Véronique; El-Mortada, Firas; Pépin, Geneviève; Germain, Marc
Most cells constitutively secrete mitochondrial DNA and proteins in...
Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease
Boardman, Neoma T; Trani, Giulia; Scalabrin, Marco; Romanello, Vanina; Wüst, Rob C I
Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the...
Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
Liang, Wenjing; Sagar, Shakti; Ravindran, Rishith; Najor, Rita H.; Quiles, Justin M.; Chi, Liguo; Diao, Rachel Y.; Woodall, Benjamin P.; Leon, Leonardo J.; Zumaya, Erika; Duran, Jason; Cauvi, David M.; De...
Impact of sphingolipids on protein membrane trafficking
Aguilera-Romero; Lucena; Sabido-Bozo; Muñiz
Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination...
Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19
Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos
COVID-19 continues to affect an unprecedented number...
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