Tulane University: "Tulane scientists uncover new pain-signaling switch"
'Researchers found that nerve cells communicate outside the cell with the enzyme vertebrate lonesome kinase (VLK), which can alter proteins in the space between neurons, affecting how those cells send signals.
“This is...
Genetic Risk Variants for Multiple Sclerosis and Other Loci Linked to Intrathecal Immunoglobulin G Synthesis
BACKGROUND AND OBJECTIVES
Intrathecal synthesis of immunoglobulin G (IgG) is a key feature of multiple sclerosis (MS) and a prognostic marker for the disease course. Although previous...
Charting the Circulating Proteome in ME/CFS: Cross System Profiling and Mechanistic insights
August Hoel; Fredrik Hoel; Sissel Elisabeth Furesund Dyrstad; Henrique Chapola; Ingrid Gurvin Rekeland; Kristin Risa; Kine Alme; Kari Sorland; Karl Albert Brokstad; Hans-Peter Marti; Olav Mella; Oystein...
Preprint. Now published - see post #18
This is from Maureen Hanson's group.
Abstract
In healthy individuals, physical exercise improves cardiovascular health and muscle strength, alleviates fatigue, and reduces risk of chronic diseases. Although exercise is suggested as a lifestyle...
Abstract
Ephs and ephrins are membrane-bound proteins that interact to modulate axon growth and neuronal function. We tested the hypothesis that eph/ephrin interactions affected the growth and function of vascular sympathetic innervation. Using RT-PCR analyses, we detected both classes of ephs...
Abstract
Post-acute sequelae of COVID-19, commonly known as long-COVID, is defined as a persistent symptom(s) that is unexplainable by alternative diagnosis and lasts beyond three months after the onset of COVID-19. Several studies have now identified long-COVID in >50% of COVID-19 patients...
I've been interested in ciguatera for a while, because exposure to the ciguatoxin can cause long term symptoms that have a lot of similarities with those of ME/CFS. And also because early on in my illness I saw a paper by a Japanese researcher that found similarities in protein expression, I...
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