-
New Forum Software Installed (Still a few issues but reopening the forum) More details.
endothelial dysfunction
-
Preprint Virus-Induced Endothelial Senescence as a Cause and Driving Factor for ME/CFS and Long COVID: Mediated by a Dysfunctional Immune System, 2025, Nunes +
Virus-Induced Endothelial Senescence as a Cause and Driving Factor for ME/CFS and Long COVID: Mediated by a Dysfunctional Immune System Massimo Nunes, Loren Kell, Anouk Slaghekke, Rob Wüst, Burtram Fielding, Douglas Kell, Etheresia Pretorius Abstract Myalgic encephalomyelitis/chronic fatigue...- hotblack
- Thread
- endothelial cells endothelial dysfunction kell long covid pretorius rob wust senescence
- Replies: 2
- Forum: ME/CFS research
-
Review Variability in Arterial Stiffness and Vascular Endothelial Function After COVID-19 […]—Systematic Review and Meta-Analysis, 2025, Loboda+
Variability in Arterial Stiffness and Vascular Endothelial Function After COVID-19 During 1.5 Years of Follow-Up—Systematic Review and Meta-Analysis Loboda, Danuta; Golba, Krzysztof S.; Gurowiec, Piotr; Bredelytė, Aelita; Razbadauskas, Artūras; Sarecka-Hujar, Beata Increasing long-term...- SNT Gatchaman
- Thread
- arterial stiffness endothelial dysfunction endothelium flow-mediated dilation systematic review vascular
- Replies: 0
- Forum: Long Covid research
-
CircSARS-CV2-N1368 from SARS-CoV-2 impairs endothelial cell function through the upregulation of ATF7 to activate TLR4/NF-κB/ROS signaling, 2025, Wen+
CircSARS-CV2-N1368 from SARS-CoV-2 impairs endothelial cell function through the upregulation of ATF7 to activate TLR4/NF-κB/ROS signaling Wen, Yi-hong; Zhao, Heng-li; Wu, Shao-yu; Jiang, Jia-xue; Gao, Yuan; Wang, Zi-fan; Liu, Xiao-yao; Yu, Fei; Ou, Tao; Zhao, An-zhi; Chen, Li-wen; Fang...- SNT Gatchaman
- Thread
- atf7 endothelial cells endothelial dysfunction micro-rna nf-κb reactive oxygen species tlr-4 toll-like receptor
- Replies: 0
- Forum: Long Covid research
-
Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics, 2025,Talkington+
Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics Talkington, Grant McGee; Kolluru, Paresh; Gressett, Timothy E.; Ismael, Saifudeen; Meenakshi, Umar; Acquarone, Mariana; Solch-Ottaiano, Rebecca J.; White, Amanda...- SNT Gatchaman
- Thread
- coagulation endothelial dysfunction gut microbiome imaging mri neuroimmune neuroinflammation pet scan ultrasound vascular
- Replies: 2
- Forum: Long Covid research
-
ME Research UK. Endothelial dysfunction in ME/CFS – our articles
The endothelium – a thin layer of cells lining every blood vessel – plays a pivotal role in regulating blood flow, blood clotting, and inflammatory responses. Research suggests that ME/CFS may involve damage to the endothelium leading to endothelial dysfunction (improper functioning of the...- John Mac
- Thread
- endothelial dysfunction meruk
- Replies: 0
- Forum: ME/CFS research news
-
Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells, 2024, Gultom et al.
Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells Gultom, Mitra; Lin, Lin; Brandt, Camilla Blunk; Milusev, Anastasia; Despont, Alain; Shaw, Jane; Döring, Yvonne; Luo, Yonglun; Rieben, Robert Severe acute respiratory syndrome coronavirus 2...- SNT Gatchaman
- Thread
- coagulation complement endothelial cells endothelial dysfunction spike protein tnf vascular
- Replies: 0
- Forum: Long Covid research
-
Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients, 2024, Tilikete et al
Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...- forestglip
- Thread
- acute infection cytokines dyspnea endothelial dysfunction fatigue ifny il-10 il-12p70 il-1a il-1b il-27 il-6 il-8 inflammation ip-10 long covid mcp-1 memory tnfa
- Replies: 0
- Forum: Long Covid research
-
[PACS]: prevalence of peripheral microvascular endothelial dysfunction and associations with NT-proBNP dynamics, 2024, Stahlberg et al
Background Post-acute COVID-19 syndrome (PACS) has been linked to microvascular endothelial dysfunction as a potential underlying pathomechanism and can manifest even following a mild course of the initial infection. Prevalence of microvascular endothelial dysfunction and circulating natriuretic...- Nightsong
- Thread
- endopat endothelial dysfunction long covid nt-probnp pacs
- Replies: 1
- Forum: Long Covid research
-
Follow-up assessment of the microvascular function in patients with long COVID, 2025, Romanowska-Kocejko et al.
Follow-up assessment of the microvascular function in patients with long COVID Romanowska-Kocejko; Braczko; Jędrzejewska; Żarczyńska-Buchowiecka; Kocejko; Kutryb-Zając; Hellmann Long COVID is a complex pathophysiological condition. However, accumulating data suggests that COVID-19 is a systemic...- SNT Gatchaman
- Thread
- adma arginine endothelial dysfunction hif-1 microcirculation nitric oxide sdma
- Replies: 2
- Forum: Long Covid research
-
Preprint Inhibition of HIF-2α Pathway as a Potential Therapeutic Strategy for Endothelial Dysfunction in Post-COVID Syndrome, 2024, Ribeiro et al.
Inhibition of HIF-2α Pathway as a Potential Therapeutic Strategy for Endothelial Dysfunction in Post-COVID Syndrome Andrea Ribeiro; Timon Kuchler; Maciej Lech; Javier Carbajo-Lozoya; Kristina Adorjan; Hans Christian Stubbe; Martina Seifert; Anna Wöhnle; Veronika Kesseler; Johanna Negele; Uwe...- SNT Gatchaman
- Thread
- endothelial dysfunction hif-1 hif-2 nitric oxide reactive oxygen species spike protein vegf
- Replies: 5
- Forum: Long Covid research
-
Less Deformable Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease (Caruso et al 2024)
Emory University School of Medicine, Atlanta, Georgia, United States. Full text links . 2024 Aug 23 DOI: 10.1182/blood.2024024608 Abstract Sickle cell disease (SCD) is canonically characterized by reduced red blood cell (RBC) deformability leading to microvascular obstruction and...- Murph
- Thread
- endothelial dysfunction red blood cell deformability
- Replies: 5
- Forum: Other health news and research
-
Impaired instructive and protective barrier functions of the endothelial cell glycocalyx pericellular matrix is impacted in COVID…, 2024
Impaired instructive and protective barrier functions of the endothelial cell glycocalyx pericellular matrix is impacted in COVID-19 disease M. Smith Margaret; James Melrose The aim of this study was to review the roles of endothelial cells in normal tissue function and to show how COVID-19...- SNT Gatchaman
- Thread
- endothelial cells endothelial dysfunction glycocalyx tight junction
- Replies: 0
- Forum: Long Covid research
-
Review Long COVID science, research and policy, 2024, Al-Aly, Davis, McCorkell, Iwasaki, Topol+
Long COVID science, research and policy Al-Aly, Ziyad; Davis, Hannah; McCorkell, Lisa; Soares, Letícia; Wulf-Hanson, Sarah; Iwasaki, Akiko; Topol, Eric J. Long COVID represents the constellation of post-acute and long-term health effects caused by SARS-CoV-2 infection; it is a complex...- SNT Gatchaman
- Thread
- complement economic impact endothelial dysfunction immune dysregulation mitochondrial dysfunction
- Replies: 17
- Forum: Long Covid research
-
Review Clinical Implications of COVID-19-Related Endothelial Dysfunction, 2024, Aljadah et al.
Clinical Implications of COVID-19-Related Endothelial Dysfunction Aljadah; Khan; Beyer; Chen; Blanker; Widlansky Endothelial dysfunction represents a measurable and early manifestation of vascular disease. Emerging evidence suggests cardiovascular risk remains elevated after COVID-19 infection...- SNT Gatchaman
- Thread
- cardiovascular disease endothelial dysfunction gut microbiome
- Replies: 0
- Forum: Long Covid research
-
Lipid Variability Induces Endothelial Dysfunction by Increasing Inflammation and Oxidative Stress, 2024, Rhee et al
Abstract Background This study investigates the impact of fluctuating lipid levels on endothelial dysfunction. Methods Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...- Andy
- Thread
- atp cardiovascular complications endothelial dysfunction inflammation lipids mitochochria nitric oxide oxidative stress
- Replies: 1
- Forum: Other health news and research
-
Review Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches, 2024, Molnar et al.
Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Molnar, Tihamer; Lehoczki, Andrea; Fekete, Monika; Varnai, Reka; Zavori, Laszlo; Erdo-Bonyar, Szabina; Simon, Diana; Berki, Tímea; Csecsei, Peter; Ezer, Erzsebet The COVID-19 pandemic, caused...- SNT Gatchaman
- Thread
- endothelial dysfunction hungary long covid mitochondria oxidative stress peroxiredoxin
- Replies: 2
- Forum: Long Covid research
-
Red Blood Cell Adenylate Energetics Is Related to Endothelial and Microvascular Function in Long COVID, 2024, Romanowska-Kocejko et al.
Red Blood Cell Adenylate Energetics Is Related to Endothelial and Microvascular Function in Long COVID Romanowska-Kocejko, Marzena; Jędrzejewska, Agata; Braczko, Alicja; Stawarska, Klaudia; Król, Oliwia; Frańczak, Marika; Harasim, Gabriela; Smoleński, Ryszard T.; Hellmann, Marcin; Kutryb-Zając...- SNT Gatchaman
- Thread
- adma adp atp endothelial dysfunction microvascular dysfunction nitric oxide oxygen oxygen extraction rbc sdma
- Replies: 0
- Forum: Long Covid research
-
Indole-3-propionic Acid, a Gut Microbiota-Derived Tryptophan Metabolite, Promotes Endothelial Dysfunction …, 2024, Geddo et al.
Indole-3-propionic Acid, a Gut Microbiota-Derived Tryptophan Metabolite, Promotes Endothelial Dysfunction Impairing Purinergic-Induced Nitric Oxide Release in Endothelial Cells Geddo, Federica; Antoniotti, Susanna; Gallo, Maria Pia; Querio, Giulia Different gut microbiota-derived metabolites...- SNT Gatchaman
- Thread
- aryl hydrocarbon receptor atp endothelial dysfunction endothelium gut microbiome indole-3-propionic acid nitric oxide tryptophan
- Replies: 2
- Forum: Other health news and research
-
COVID-19-related retinal microvasculopathy and systemic implications in patients with severe disease: results from the Methuselah study, 2024, Castell
COVID-19-related retinal microvasculopathy and systemic implications in patients with severe disease: results from the Methuselah study Castellino, Niccolò; Longo, Antonio; Russo, Andrea; Bonfiglio, Vincenza; Fallico, Matteo; Toro, Mario Damiano; Cappellani, Francesco; Grillo, Marco; Gaudio...- SNT Gatchaman
- Thread
- aorta endothelial dysfunction long covid optical coherence tomography renal retinal capillary microcirculation
- Replies: 1
- Forum: Long Covid research
-
Long-Term Microvascular Changes in Multisystem Inflammatory Syndrome in Children, 2024, Boever et al.
Long-Term Microvascular Changes in Multisystem Inflammatory Syndrome in Children Julie Boever; Claudia Nussbaum; Leonie Arnold; Nikolaus A. Haas; Simone K. Dold; Felix S. Oberhoffer; André Jakob No Abstract. Videos of sublingual microcirculation were obtained with a handheld MicroScan video...- SNT Gatchaman
- Thread
- capillaries capillary endopat endothelial dysfunction microcirculation mis-c
- Replies: 0
- Forum: Long Covid research