dementia

https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(25)00118-4/fulltext Summary Background A rapidly evolving evidence base suggests that exposure to outdoor air pollution is a risk factor for the onset of dementia, with an upturn in publications since 2022. We sought to synthesise...

Abstract The root causes of dementia are still largely unclear, and the medical community lacks highly effective preventive and therapeutic pharmaceutical agents for dementia despite large investments into their development. There is growing interest in the question if infectious agents play a...

https://www.news-medical.net/news/20250701/Clinical-trial-examines-whether-Ambroxol-can-slow-dementia-in-people-with-Parkinsons.aspx research paper: https://jamanetwork.com/journals/jamaneurology/article-abstract/2835760

This CKS, NICE document relating to Differential diagnosis entitled Dementia; What else could it be? raises several alternative diagnoses but no mention of ME/CFS. Differential diagnosis | Diagnosis | Dementia | CKS | NICE Particularly as we get older, any cognitive issues, (classic for ME...

Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial Jiang He, Chuansheng Zhao, Shanshan Zhong, Nanxiang Ouyang, Guozhe Sun, Lixia Qiao, Ruihai Yang, Chunxia Zhao, Huayan Liu, Weiyu Teng, Xu Liu...

Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study Yuxia Li, Luyao Wang, Jiayi Zhong, Huanyu Xu, Ying Han, Chuantao Zuo, Jiehui Jiang Background: Subjective cognitive decline (SCD) has been recognized as a potential risk stage for...

The recombinant shingles vaccine is associated with lower risk of dementia Quentin Dercon, John A. Todd, John A. Todd, Paul J. Harrison Published: 25 July 2024 Abstract There is emerging evidence that the live herpes zoster (shingles) vaccine might protect against dementia. However, the...

A Possible Reversible Cause of Cognitive Impairment: Undiagnosed Cirrhosis and Potential Hepatic Encephalopathy in Patients with Dementia Scott Silvey, Richard Sterling, Evan French, Michael Godschalk, Angela Gentili, Nilang Patel, Jasmohan Bajaj Background Dementia and hepatic encephalopathy...

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies Authors Abstract Importance Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD], dementia with Lewy bodies [DLB], multiple system...

Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons Abstract COVID-19 has represented an issue for global health since its outbreak in March 2020. It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients Maxime Taquet, PhD; Rebecca Sillett, BA; Lena Zhu, BS; Jacob Mendel, MMath; Isabella Camplisson, BS; Quentin Dercon, MSc; Paul J Harrison...

Abstract As one of the leading causes of dementia, Alzheimer’s disease (AD) is a condition in which individuals experience progressive cognitive decline. Although it is known that beta-amyloid (Aβ) deposits and neurofibrillary tangles (NFT) of tau fibrils are hallmark characteristics of AD, the...

Abstract Much of human behaviour is motivated by the drive to experience pleasure. The capacity to envisage pleasurable outcomes and to engage in goal-directed behaviour to secure these outcomes depends upon the integrity of frontostriatal circuits in the brain. Anhedonia refers to the...

https://www.theguardian.com/science/2020/oct/25/the-dementia-that-can-be-cured The dementia that can be cured Treatments mentioned include steroids, rituximab and plasma exchange.

Prilosec Why is this statement significant for patients with Lewy Body Disease? (LBD) Because this OTC signals the brain to turn off the proton pump in the stomach. Apparently for LBD patients, changing brain signals pushes the patients into the disease. My sister related this information to...

https://neurosciencenews.com/inflammation-drugs-dementia-15285/

https://www.alzheimers.org.uk/blog/late-new-type-dementia New type of dementia discovered

Thought this was relevant since @Jonathan Edwards has mentioned gait as a possible diagnostic tool in ME. Link: https://www.alzheimersanddementia.com/article/S1552-5260(19)35120-9/fulltext

https://m.medicalxpress.com/news/2018-10-machine-uncovers-dementia-subtypes-implication.html Just thought this was interesting in relation to how subtypes are being found in other illness.

https://www.sciencedaily.com/releases/2018/10/181015084602.htm