cytokines

https://www.mdpi.com/2227-9059/13/5/1200 Abstract Background/Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifaceted and diverse disorder with an ambiguous etiology. Recent evidence indicates that immune system impairment and inflammatory mechanisms are pivotal...

[ Embargoed PhD thesis; abstract only. ] Abstract Background: Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a disabling multisystem complex disorder with no known etiology or approved treatment. Our studies aimed to assess the link between ME/CFS and autoimmune disease (AID)...

Effects of a mild inflammatory challenge on cytokines and sickness behavior: A randomized controlled trial using the influenza vaccine Jolink; Feldman; Antenucci; Cardenas; West; Nakamura; Muscatell The influenza vaccine has reliably been associated with mild, within-person increases in...

SARS-CoV-2 Viral Load and Cytokine Dynamics Profile as Early Signatures of Long COVID Condition in Hospitalized Individuals Jacobo Alonso Domínguez; Inés Martínez Barros; Irene Viéitez; Mercedes Peleteiro; Beatriz Calderón-Cruz; José A. González-Nóvoa; Alexandre Pérez González; Virginia Leiro...

2015 study Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome Mangalathu S. Rajeevan, Irina Dimulescu, Janna Murray 1, Virginia R. Falkenberg, Elizabeth R. Unger Abstract Recent evidence suggests immune and inflammatory alterations are...

Abstract: This study aimed to identify signalling and metabolic pathways significantly impacted by alterations in cytokine and metabolic levels in response to acute cold exposure (CWI) following rest and exercise. In line with some previous studies, acute exposure to cold and exercise...

Abstract: Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness. Clarifying the way the brain processes information generated by the innate immune system is accompanied by a progressive elucidation of the cellular and...

Enhanced Gene Expression Following Vaccination in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Ekua W Brenu, Gunn M Atkinson, Mieke L van Driel, Sanne Kreijkamp-Kaspers, Don R Staines, Sonya M Marshall-Gradisnik Abstract Vaccines have been shown to cause differential expression of genes...

Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...

Abstract Evidence linking the endothelium to cardiac injury in long coronavirus disease (COVID) is well documented, but the underlying mechanisms remain unknown. Here we show that cytokines released by endothelial cells (ECs) contribute to long-COVID-associated cardiac dysfunction. Using...

Bruce K. Patterson, Jose Guevara-Coto, Javier Mora, Edgar B. Francisco, Ram Yogendra, Rodrigo A. Mora-Rodríguez, Christopher Beaty, Gwyneth Lemaster, Gary Kaplan DO, Amiram Katz & Joseph A. Bellanti Abstract The absence of a long COVID (LC) or post-acute sequelae of COVID-19 (PASC)...

Cytokine Profile in Patients with Postacute Sequelae of COVID-19 Nathalie Ghorra; Alexandros Popotas; Tatiana Besse-Hammer; Anne Rogiers; Francis Corazza; Carole Nagant The enduring impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease manifestation, COVID-19...

Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...

Chronic fatigue syndrome and circulating cytokines: A systematic review S Blundell, KK Ray, M Buckland, PD White There has been much interest in the role of the immune system in the pathophysiology of chronic fatigue syndrome (CFS), as CFS may develop following an infection and cytokines are...

https://pubmed.ncbi.nlm.nih.gov/38808863/ Abstract Background: Over 30% of patients with COVID-19 have persistent symptoms that last beyond 30 days and referred to as Long COVID. Long COVID has been associated with a persistent elevation in peripheral cytokines including interleukin-6...

Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content Gerdle, Björn; Dahlqvist Leinhard, Olof; Lund, Eva; Lundberg, Peter; Forsgren...

Now published: Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect function of stem cell derived cardiomyocytes, 2024, Sinclair+']link here[/URL] Preprint Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of...

Chloride Homeostasis Regulates cGAS-STING Signaling Jared Morse; Danna Wang; Serena Mei; Danielle Whitham; Colby Hladun; Costel C. Darie; Herman O Sintim; Modi Wang; KaHo Leung The cGAS-STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride...

[In mice] Introduction: Post-infection syndromes are characterised by fatigue, muscle pain, anhedonia, and cognitive impairment; mechanistic studies exploring these syndromes have focussed on pathways downstream of Toll-like receptor (TLR) 4 activation. Here, we investigated the mechanistic...

Persistent immune abnormalities discriminate post-COVID syndrome from convalescence Sbierski-Kind, Julia; Schlickeiser, Stephan; Feldmann, Svenja; Ober, Veronica; Grüner, Eva; Pleimelding, Claire; Gilberg, Leonard; Brand, Isabel; Weigl, Nikolas; Ahmed, Mohamed I. M.; Ibarra, Gerardo; Ruzicka...