covid

SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling Perico, Luca; Morigi, Marina; Pezzotta, Anna; Locatelli, Monica; Imberti, Barbara; Corna, Daniela; Cerullo, Domenico; Benigni, Ariela; Remuzzi, Giuseppe The...

Investigating the ‘Bolsonaro effect’ on the spread of the Covid-19 pandemic: an empirical analysis of observational data in Brazil Mireille Razafindrakoto; François Roubaud; Marta Reis Castilho; Valéria Pero; João Saboia Brazil counts among the countries the hardest hit by the Covid-19...

New Air Monitor Can Detect COVID Virus in 5 Minutes https://www.webmd.com/covid/news/20230710/new-air-monitor-can-detect-covid-five-minutes

Cellular microRNAs target SARS-CoV-2 spike protein and restrict viral replication Kishore Vaddadi ; Chaitanya Gandikota ; Chaoqun Huang ; Yurong Liang ; Lin Liu MicroRNAs (miRNAs) regulate gene expression post-transcriptionally and are implicated in viral replication and host tropism...

3 Years Into Long COVID: Where Do We Go From Here? https://www.medscape.com/viewarticle/993827 "... approximately 6% of all US adults are currently experiencing long COVID, with Hispanic/Latinx individuals, transgender individuals, and cis female individuals facing the highest rates."...

The post-viral fatigue syndromes long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) have multiple, potentially overlapping, pathological processes. These include persisting reservoirs of virus e.g. SARS-CoV-2 in long COVID patient's tissues, immune dysregulation with or...

Increased red blood cell deformation in children and adolescents after SARS-CoV-2 infection Eder, Julian; Schumm, Leonie; Armann, Jakob P.; Puhan, Milo A.; Beuschlein, Felix; Kirschbaum, Clemens; Berner, Reinhard; Toepfner, Nicole Severe coronavirus disease 2019 (COVID-19) is associated with...

Metformin reduces SARS-CoV-2 in a Phase 3 Randomized Placebo Controlled Clinical Trial Carolyn T Bramante; Kenneth B Beckman; Tanvi Mehta; Amy B Krager; David J Odde; Christopher J Tignanelli; John B Buse; Darnell M Johnson; Ray H B Watson; Jerry J Daniel; David M Liebovitz; Jacinda M Nicklas...

Discontinuation of Universal Admission Testing for SARS-CoV-2 and Hospital-Onset COVID-19 Infections in England and Scotland Theodore R. Pak; Chanu Rhee; Rui Wang; Michael Klompas Link | PDF (JAMA Internal Medicine)

Access to individual patient-level data (IPD) of randomized clinical trials (RCTs) increases the reproducibility of research, facilitates exploration of effect modifiers, and leverages research investments beyond the original research question. This study aimed to describe access to IPD of RCTs...

Perceived Cognitive Deficits in Patients With Symptomatic SARS-CoV-2 and Their Association With Post–COVID-19 Condition Teresa C. Liu, Sun M. Yoo, Myung. S. Sim, Yash Motwani, Nisha Viswanathan, Neil S. Wenger Abstract Importance Neuropsychiatric symptoms are common in acute SARS-CoV-2...

(Oh the irony) More than 30 people who attended a conference organized by the CDC's "disease detectives" likely were infected with COVID-19 at the event last week, the agency said. The CDC hosted the 4-day conference that started April 24 at a Crowne Plaza hotel just outside Atlanta, which is...

Cardiopulmonary, Functional, Cognitive and Mental Health Outcomes Post-COVID-19, Across the Range of Severity of Acute Illness, in a Physically Active, Working-Age Population Oliver O’Sullivan, David A. Holdsworth, Peter Ladlow, Robert M. Barker-Davies, Rebecca Chamley, Andrew Houston, Samantha...

Preprint Incident autoimmune diseases in association with a SARS-CoV-2 infection: A matched cohort study Falko Tesch, Franz Ehm, Annika Vivirito, Danny Wende, Manuel Batram, Friedrich Loser, Simone Menzer, Josephine Jacob, Martin Roessler, Martin Seifert, Barbara Kind, Christina König, Claudia...

Link and abstract of the study is posted later in the thread, here. BBC: Covid: No evidence shielding helped - Swansea uni study quote: Swansea University compared 117,000 people shielding in Wales with the rest of the population of three million. The study found deaths and healthcare usage...

Journal of Biomedical Informatics PASCLex: A comprehensive post-acute sequelae of COVID-19 (PASC) symptom lexicon derived from electronic health record clinical notes Liqin Wang, Dinah Foer, Erin MacPhaul, Ying-Chih Lo, David W. Bates, Li Zhou Abstract Objective To develop a comprehensive...

[Moderators - This article is about COVID-19 reinfection. I posted in the Long Covid forum because of the final section that talks about Long Covid. But please move it if it belongs elsewhere.] What doctors wish patients knew about COVID-19 reinfection...

People who haven't had COVID will likely catch XBB.1.5 – and many will get reinfected, experts say Variant XBB.1.5 is very contagious, meaning everyone is at risk even if you've already been infected. As the U.S. enters year 3 of the pandemic, here's an update on the state of COVID. KAREN...

CDC Maps: From Red to Green Comparison of two of the CDC maps (community transmission vs community levels) that are available on the CDC website and displayed on their social media. FYI, this video is new, and the discussion is timely, even though the CDC made these map changes to show new...

Some threads have been merged to create this news thread The future of the NHS: no longer the envy of the world? Picked up from social media. Article in the Lancet London School of Economics have this project with an independent commission looking to identify big challenges faced by the NHS...