Proteomic and metabolomic profiling of plasma uncovers immune responses in patients with Long COVID-19
Yulin Wei, Hongyan Gu, Jun Ma, Xiaojuan Mao, Bing Wang, Weiyan Wu, Shimin Yu, Jinyuan Wang, Huan Zhao, yanbin he
[Preprint]
Abstract
Long COVID is an often-debilitating condition with...
Proteomic analysis of post-COVID condition: Insights from plasma and pellet blood fractions
Alejandro Seco-González, Paula Antelo-Riveiro, Susana B. Bravo, P.F. Garrido, M.J. Domínguez-Santalla, E. Rodríguez-Ruiz, Á. Piñeiro, R. Garcia-Fandino
Background
Persistent symptoms extending beyond...
2015 study
Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome
Mangalathu S. Rajeevan, Irina Dimulescu, Janna Murray 1, Virginia R. Falkenberg, Elizabeth R. Unger
Abstract
Recent evidence suggests immune and inflammatory alterations are...
Abstract:
The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been...
ABSTRACT
The complement system is a vital anti-microbial defence mechanism against circulating pathogens. Excessive complement activation can have deleterious outcomes for the host and is consequently tightly modulated by a set of membrane-associated and fluid-phase regulators of complement...
Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery
Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius
Published 16 July 2024
Abstract
Myalgic...
coagulation
complementcomplement component 9
complementsystem
endothelial function
immunoglobulin
kell
lactotransferrin
liquid chromatography tandem mass spectroscopy
me/cfs
platelet factor 4
platelet-poor plasma
pretorius
protein s
s100
s100-a9
thrombospondin-1
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
Open access: https://www.science.org/doi/10.1126/science.adg7942
Editor’s summary
Some individuals can endure persistent, debilitating symptoms for many months after an initial severe acute respiratory...
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.