cognitive dysfunction

Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...

Pre-print (free access) Abstract Extensive research links regular physical exercise to an overall enhancement of cognitive function across the lifespan. Here, we assess the causal evidence supporting this relationship in the healthy population, using an umbrella review of meta-analyses limited...

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome Maria Díez-Cirarda; Miguel Yus-Fuertes; Rafael Sanchez-Sanchez; Javier J. Gonzalez-Rosa; Gabriel Gonzalez-Escamilla; Lidia Gil-Martínez; Cristina Delgado-Alonso...

3 Years Into Long COVID: Where Do We Go From Here? https://www.medscape.com/viewarticle/993827 "... approximately 6% of all US adults are currently experiencing long COVID, with Hispanic/Latinx individuals, transgender individuals, and cis female individuals facing the highest rates."...

Neuropsychological deficits in patients with persistent COVID-19 symptoms: a systematic review and meta-analysis Sobrino-Relaño, Saioa; Balboa-Bandeira, Yolanda; Peña, Javier; Ibarretxe-Bilbao, Naroa; Zubiaurre-Elorza, Leire; Ojeda, Natalia Long-term persistent symptoms of COVID-19 affect...

Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome: a cross-sectional observational study Sarah Walker; Henry Goodfellow; Patra Pookarnjanamorakot; Elizabeth Murray; Julia Bindman; Ann Blandford; Katherine Bradbury; Belinda Cooper...

Full title: Cognitive functioning in postural orthostatic tachycardia syndrome among different body positions: a prospective pilot study (POTSKog study) Abstract Purpose Approximately 96% of patients with postural orthostatic tachycardia syndrome (PoTS) report cognitive complaints. We...

Now published - link here ********* Preprint Association of Baseline Cerebrovascular Reactivity and Development of Enlarged Perivascular Spaces in the Basal Ganglia Timothy J Libecap; Christopher E Bauer; Valentinos Zachariou; Colleen A Pappas; Flavius D Raslau; Peiying Liu; Hanzhang Lu; Brian...

Sylvester, R. et al. (2021) The Queen Square Brain Injury Clinic, ACNR. https://acnr.co.uk/articles/the-queen-square-brain-injury-clinic/ Abstract There is recognition of the need for rehabilitation after TBI, but less for expert diagnosis at the level of pathology and impairment during...

Neurocognitive and psychiatric symptoms following infection with COVID-19: Evidence from laboratory and population studies Hall PA, Ayaz H, Meng G, Hudson A, Sakib MN, Quah ACK, Agar TK, Lee JA, Boudreau C, Fong GT Objective: The objective of the current investigation was to examine...

Authors: Fabricia L. Fontes-Dantas et al Highlights Spike protein infusion into mouse brain induces late cognitive dysfunction Spike protein induces late hippocampal microgliosis and synapse loss Blockage of TLR4 renders mice resistant to Spike-induced cognitive dysfunction TLR4-2604G>A GG...

Every time the disability of ME/CFS is portrayed as people who were once physically active in life (often athletes) who can no longer reach the physical performance that they used to have. In severe cases, it's housebound or bedbound patients who "struggle to take a shower" or "can't go out for...

Free full text: https://library.oapen.org/bitstream/handle/20.500.12657/58162/9781003257318_10.4324_9781003257318-5.pdf?sequence=1

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients Maxime Taquet, PhD; Rebecca Sillett, BA; Lena Zhu, BS; Jacob Mendel, MMath; Isabella Camplisson, BS; Quentin Dercon, MSc; Paul J Harrison...

Highlights Cognitive fatigue is explored with magnetic resonance spectroscopy during a workday Hard cognitive work leads to glutamate accumulation in the lateral prefrontal cortex The need for glutamate regulation reduces the control exerted over decision-making Reduced control favors the...

Abstract Primary Sjögren’s syndrome (pSS) is an autoimmune disease with frequent neurological involvement. Memory complaints are common, but their precise patterns remain unclear. We wanted to characterize patterns of neurocognitive profiles in pSS patients with cognitive complaints. Only pSS...

Abstract In addition to chronic widespread pain and depression and anxiety symptoms, patients with fibromyalgia frequently experience cognitive problems. This study investigated executive functions in fibromyalgia via a Go/No-Go task. To obtain comprehensive information about performance...

Abstract People recovered from COVID-19 may still present complications including respiratory and neurological sequelae. In other viral infections, cognitive impairment occurs due to brain damage or dysfunction caused by vascular lesions and inflammatory processes. Persistent cognitive...

Gut microbiota from patients with mild COVID-19 cause alterations in mice that resemble post-COVID syndrome Viviani Mendes de Almeida, Daiane F Engel, Mayra Fernanda Ricci, Clênio Silva Cruz, Icaro Santos Lopes, Daniele Almeida Alves, Mirna d’ Auriol, João Magalhães, Giuliana S. Zuccoli, Bradley...

Aussie breakthrough on the long Covid condition that leaves sufferers with symptoms similar to 'traumatic brain injury (Daily Mail - no really) (Kynurenine) ETA: Dr Bruce Brew recently co-authored Recent advances in clinical trials targeting the kynurenine pathway (Pires et al, 2021)