Abstract:
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating condition with a large proportion of patients that experience orthostatic intolerance (OI). This systematic review aimed to assess whether cerebral blood flow (CBF) is reduced in ME/CFS...
Dynamic cerebral autoregulation in people with mild cognitive impairment
Laura K Fitzgibbon-Collins; Michael Borrie; Sue Peters; J Kevin Shoemaker; Jaspreet Bhangu
Altered cerebrovascular hemodynamics and low cerebral perfusion contribute to the development and progression of dementia. Dynamic...
Abstract
Background/Objectives: Orthostatic intolerance is prevalent in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and is caused by an abnormal reduction in cerebral blood flow (CBF). In healthy controls (HCs), CBF is regulated complexly, and cardiac output (CO) is...
Cerebral hemodynamics to acute exercise in Veterans with Gulf War Illness
Grace E. Branchaw
Committee Members:
Dr. Dane Cook, Chair
Dr. Jill Barnes
Dr. Jee-Seon Kim
[Line breaks added]
Introduction
Gulf War Illness (GWI) is a chronic multisymptom illness (CMI) affecting approximately one...
Post-Concussion Brain Changes Relative to Pre-Injury White Matter and Cerebral Blood Flow
Nathan W. Churchill, Michael G. Hutchison, Simon J. Graham, Tom A. Schweizer
BACKGROUND AND OBJECTIVES
Medical clearance for return to play (RTP) after sports-related concussion is based on clinical...
Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women
Michelle E. Favre; Valerie Lim; Michael J. Falvo; Jorge M. Serrador
Cerebrovascular reactivity and cerebral autoregulation are two major mechanisms that...
Abstract
Cerebral blood flow (CBF) is vital for delivering oxygen and nutrients to the brain. Many forms of orthostatic intolerance (OI) involve impaired regulation of CBF in the upright posture, which results in disabling symptoms that decrease quality of life.
Because CBF is not easy to...
Respiratory influence on cerebral blood flow and blood volume – A 4D flow MRI study
Pontus Söderström; Anders Eklund; Nina Karalija; Britt M Andersson; Katrine Riklund; Lars Bäckman; Jan Malm; Anders Wåhlin
Variations in cerebral blood flow and blood volume interact with intracranial pressure...
Abstract
Cognitive dysfunction is frequently reported in individuals with postural orthostatic tachycardia syndrome (POTS), possibly resulting from reduced cerebral blood flow (CBF).
We used brain SPECT, an accessible imaging modality that has not been systematically evaluated in this patient...
Correlates of asymmetric venous drainage in resting state functional magnetic resonance imaging data
Nastaran Schwarz; Benedikt Sundermann; Christian Mathys
Functional magnetic resonance imaging (fMRI) is an indirect technique for measuring cerebral neural activity. It depends on the local...
Peter Novak and David Systrom, etc. Peter Rowe is a reviewer…
one quote from the paper:
Our study provides additional evidence of importance of cerebral blood flow and respiratory system in orthostatic intolerance syndromes without orthostatic hypotension...
Assessing Cerebral Microvascular Volumetric Pulsatility with High-Resolution 4D CBV MRI at 7T
Fanhua Guo; Chenyang Zhao; Qinyang Shou; Ning Jin; Kay Jann; Xingfeng Shao; Danny JJ Wang
Arterial pulsation is crucial for promoting fluid circulation and for influencing neuronal activity. Previous...
Highlights
POTS causes cardiovascular instability and severe symptoms.
Postural hyperventilation is thought to cause POTS, but the mechanisms are unclear.
Reduced stroke volume and brain perfusion drive postural hyperventilation in POTS.
Stroke volume and brain perfusion should be targeted as...
Abstract
Neuroimaging studies have indicated that altered cerebral blood flow (CBF) was associated with the long-term symptoms of postacute sequelae of SARS-CoV-2 infection (PASC), also known as “long COVID”. COVID-19 and long COVID were found to be strongly associated with host gene expression...
Brain cerebral blood flow with MRI-visible enlarged perivascular space in adults
Chunyan Yu; Baijie Wang; Qiyuan Sun; Huiyan Huo; Lingyan Zhang; Du Hongyan
OBJECTIVES
To explore the correlation between enlarged perivascular spaces (EPVS) in the basal ganglia (BG-EPVS) and centrum semiovale...
Published
Link here: Cardiac Output–Cerebral Blood Flow Relationship Is Abnormal in Most ME/CFS Patients with a Normal Heart Rate & Blood Pressure ..., 2024, van Campen
Preprint
Full title:
The cardiac output - cerebral blood flow relation is abnormal in most ME/CFS patients with a normal heart...
https://link.springer.com/article/10.1007/s10072-024-07673-8
Coelho, F.M.S., de Carvalho Cremaschi, R.M. & Novak, P. Cerebral blood flow and end-tidal CO2 predict lightheadedness during head-up tilt in patients with orthostatic intolerance. Neurol Sci (2024)...
written by: Mitchell G. Miglis, Noor Syed, Melissa M. Cortez, Frans C. Viser, C. Linda MC van Campen, Peter Novak
Unfortunately one can only see the references here:
https://link.springer.com/article/10.1007/s10286-024-01036-1
One can see the start of the letter here...
https://journals.physiology.org/doi/abs/10.1152/ajpregu.00071.2024
Research Article
Phenylephrine Alters Phase Synchronization between Cerebral Blood Velocity and Blood Pressure in Chronic Fatigue Syndrome with Orthostatic Intolerance
Marvin S. Medow* and Julian M. Stewart
29 APR...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393352/
Abstract
The purpose of this study was to investigate whether CFS patients without comorbid psychiatric diagnoses differ from CFS patients with comorbid psychiatric diagnoses and healthy control subjects in neuropsychological performance...
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