Inflammation from mild COVID-19 results in persistent neurological and behavioral changes in rhesus macaques
Although most SARS-CoV-2 infections result in mild or moderate symptoms not requiring hospitalization, many patients experience persistent symptoms after their initial recovery, a...
Association of Autonomic Dysfunction With Long COVID: Evaluation Using Quantitative Autonomic Testing
BACKGROUND
Persistent symptoms (eg, heart palpitations, lightheadedness, fatigue) despite resolution of acute COVID-19 infection is termed “long COVID syndrome” or simply “long COVID.” Long...
Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome
OBJECTIVES
To examine muscle acid handling following exercise in chronic fatigue syndrome (CFS⁄ME) and the relationship with autonomic dysfunction.
DESIGN...
Characterization of sympathicotonia in post-covid condition long covid and healthy controls using long-term electrodermal activity EDA follow-up
PURPOSE
After SARS-CoV-2 infection, some patients develop post-COVID condition (PCC), often associated with sympathicotonia. This study aimed to...
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics
Sleep deprivation rapidly disrupts cognitive function and in the long term contributes to neurological disease. Why sleep deprivation has such profound effects on...
Case-control study of autonomic symptoms in the setting of Long COVID with tilt table testing
BACKGROUND
Autonomic symptoms and orthostatic syndromes have been reported in Long COVID, but few studies have characterized findings using head up tilt table testing.
OBJECTIVE
To characterize...
Wearable heart rate variability monitoring identifies autonomic dysfunction and thresholds for post-exertional malaise in Long COVID
Twan Ruijgt, Anouk Slaghekke, Anneke Ellens, Kasper Janssen, Rob CI Wust
Objectives
Patients with Long COVID experience disabling fatigue, autonomic dysfunction...
Full title: Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19
Rebeka Fekete, Alba Simats, Eduárd Bíró, Balázs Pósfai, Csaba Cserép, Anett D. Schwarcz, Eszter Szabadits, Zsuzsanna Környei, Krisztina...
Attenuated cardiac autonomic function in patients with long-COVID with impaired orthostatic hemodynamics
Hira, Rashmin; Baker, Jacquie R.; Siddiqui, Tanya; Patel, Aishani; Valani, Felix Gabriel Ayala; Lloyd, Matthew G.; Floras, John S.; Morillo, Carlos A.; Sheldon, Robert S.; Raj, Satish R...
Organ-specific sympathetic innervation defines visceral functions
Wang, Tongtong; Teng, Bochuan; Yao, Dickson R.; Gao, Wei; Oka, Yuki
The autonomic nervous system orchestrates the functions of the brain and body through the sympathetic and parasympathetic pathways1 . However, our understanding...
Signicant Microvascular Abnormalities Are Present in Autonomic Dysfunction: Results of a Prospective Study
Sehreen Mumtaz, et. al.
Abstract
Purpose The prevalence and phenotype of capillaroscopic abnormalities in patients with autonomic nervous system dysfunction has not been investigated...
Heart rate variability is not associated with multiple chemical sensitivity in a cross-sectional population-based study-The Danish study of functional disorders
Anne Ahrendt Bjerregaard, Louise Brinth, Marie W Petersen, Signe U Schovsbo, Lene Eplov, Susanne Brix, Allan Linneberg, Lise Gormsen...
Physiological presentation and risk factors of long COVID in the UK using smartphones and wearable devices: a longitudinal, citizen science, case–control study
Callum Stewart; Yatharth Ranjan; Pauline Conde; Shaoxiong Sun; Yuezhou Zhang; Zulqarnain Rashid; Heet Sankesara; Nicholas Cummins...
Full title:
Plasma Neurofilament Light Chain: A Potential Biomarker for Neurological Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disorder characterized by heterogeneous symptoms, which lack...
Reduced Autonomic Function in Patients with Long-COVID-19 Syndrome is Mediated by Cardiorespiratory Fitness
Oscoz-Ochandorena; Legarra-Gorgoñon; García-Alonso; García-Alonso; Izquierdo; Ramírez-Vélez
BACKGROUND
Long‐COVID-19 syndrome (LCS) exhibits neurological problems such as peripheral...
Post-COVID dysautonomias: what we know and mainly what we don’t know
Goldstein, David S.
Following on from the COVID-19 pandemic is another worldwide public health challenge that is referred to variously as long COVID, post-COVID syndrome or post-acute sequelae of SARS-CoV-2 infection (PASC)...
Autonomic Manifestations of Long-COVID Syndrome
Hira, Rashmin; Karalasingham, Kavithra; Baker, Jacquie R.; Raj, Satish R.
Purpose of Review
Long-COVID is a novel condition emerging from the COVID-19 pandemic. Long-COVID is characterized by symptoms commonly seen in autonomic disorders including...
High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning
Marie-Claire Seeley; Celine Gallagher; Eric Ong; Amy Langdon; Jonathan Chieng; Danielle Bailey; Amanda Page; Han S. Lim; Dennis H...
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