autoimmune disease

Affective disorders and chronic inflammatory conditions: Analysis of 1.5 million participants in Our Future Health Arish Mudra Rakshasa-Loots, Duncan Swiffen, Christina Steyn, Katie F. M. Marwick, Daniel J. Smith [Line breaks added] Abstract Chronic inflammation is associated with psychiatric...

Long-Term Risk of Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19 Yeon-Woo Heo; Jae Joon Jeon; Min Chul Ha; You Hyun Kim; Solam Lee IMPORTANCE Few studies have investigated the association between COVID-19 and autoimmune and autoinflammatory connective tissue...

Epstein–Barr virus as a potentiator of autoimmune diseases William H. Robinson, Shady Younis, …Tobias V. Lanz Show authors Nature Reviews Rheumatology (2024)Cite this article Metricsdetails Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of autoimmune...

Prevalence and Risk Factors of Post-Acute Sequela of COVID-19 in Adults with Systemic Autoimmune Rheumatic Diseases Mayan S. Teles; Janetta Brundage; Teresa Po-Yu Chiang; Jennifer L. Alejo; Nicolas Henriquez; Rachel Wallwork; Lisa Christopher Stine; Allan Massie; Dorry L. Segev; Caoilfhionn M...

Abstract Increasing rates of autoimmune and inflammatory disease present a burgeoning threat to human health1. This is compounded by the limited efficacy of available treatments1 and high failure rates during drug development2, highlighting an urgent need to better understand disease...

MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic MIP-C Paula David; Saptarshi Sinha; Khizer Iqbal; Gabriele De Marco; Sahar Taheri; Ella McLaren; Sheetal Maisuria; Gururaj Arumugakani; Zoe Ash; Catrin Buckley; Lauren Coles; Chamila Hettiarachchi; Emma...

https://www.nature.com/articles/s41588-024-01682-1 Medical Xpress: Researchers develop statistical method for genetic mapping of autoimmune diseases Wondering if something like this could help Decode ME

Abstract Mitochondrial DNA (mtDNA) encodes essential subunits of the oxidative phosphorylation system, but is also a major damage-associated molecular pattern (DAMP) that engages innate immune sensors when released into the cytoplasm, outside of cells or into circulation. As a DAMP, mtDNA not...

https://www.sciencedirect.com/science/article/pii/S2589004223021612 Summary: Many autoimmune disorders exhibit flares in which symptoms erupt and then decline, as exemplified by multiple sclerosis (MS) in its relapsing-remitting form. Existing mathematical models of autoimmune flares often...

Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19 Sung Ha Lim; Hyun Jeong Ju; Ju Hee Han; Ji Hae Lee; Won-Soo Lee; Jung Min Bae; Solam Lee Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19 have been reported. However, their...

Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...

A novel estrogen receptor 1: sphingomyelin phosphodiesterase acid-like 3B pathway mediates rituximab response in myositis patients Parkes, Joanna E; Boehler, Jessica F; Li, Ning; Kendra, Ryan M; O’Hanlon, Terrance P; Hoffman, Eric P; Peterson, Jennifer M; Miller, Frederick W; Rider, Lisa G...

Risk of autoimmune diseases in patients with COVID-19: A retrospective cohort study Renin Chang, Thomas Yen-Ting Chen, Shiow-Ing Wang, Yao-Min Hung, Hui-Yuan Chen, Cheng-Chung James Weic Background There are a growing number of case reports of various autoimmune diseases occurring after...

I don't know if this has been posted elsewhere but I thought it was very interesting. I wonder if something like this might end up being helpful for a subset of pwME... https://www.theguardian.com/science/2022/sep/15/scientists-hail-autoimmune-disease-therapy-breakthrough-car-t-cell-lupus "In...

Abstract Primary Sjögren’s syndrome (pSS) is an autoimmune disease with frequent neurological involvement. Memory complaints are common, but their precise patterns remain unclear. We wanted to characterize patterns of neurocognitive profiles in pSS patients with cognitive complaints. Only pSS...

https://www.nature.com/articles/d41586-021-01836-9

https://web.archive.org/web/20210514071300id_/http://inpact-psychologyconference.org/wp-content/uploads/2021/05/2021inpact027.pdf Psychological Applications and Trends 2021 p-ISSN: 2184-2205 e-ISSN: 2184-3414 ISBN: 978-989-54815-5-2 © 2021 FACTORS CONTRIBUTING TO WELL-BEING: COMPARING...

Highlights • Chronic inflammation can be caused by organelle (e.g., mitochondria) malfunction. • Dysfunctional mitochondria release DAMPs that trigger inflammation through PRRs. • Salivary cells’ mitochondria show ultrastructural alterations in Sjögren’s syndrome. • Endoplasmic reticulum...

If those numbers are reliable this is a borderline epidemic level crisis. Nearly 1/5 of the UK population reporting significant cognitive symptoms interfering with daily life but are typically brushed off by medicine. The worldwide numbers would place this at above 1B. That's staggering...