An interesting read given the past TSPO-PET neuroinflammation studies on ME using first generation [11C]PK-11195 and now more recently second generation [11C]DPA-713, the pros/cons and limitations of these radioligands, and the development of novel third generation ligands.
Recent Developments...
Possibly relevant to ME given the potential involvement of both microglia in the brain and the microbiome in the illness.
The article, https://medicalxpress.com/news/2018-05-gut-neurologic-disease.amp
https://www.nature.com/articles/s41586-018-0119-x
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