antifungal

  1. R

    Anidulafungin (IV antifungal)

    Anecdotal evidence of improvement following anti-fungal treatment As some of your may recall, when Graham McPhee was in hospital with recurrent sepsis, his son @IanMcPhee reported that he had been prescribed anidulafungin (an IV antifungal drug), following which he noticed improvement in his...
  2. E

    Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19, 2023, Iliev et al

    Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 Gastrointestinal fungal dysbiosis is a hallmark of several diseases marked by systemic immune activation. Whether persistent pathobiont colonization during immune alterations and...
  3. D

    Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation, 2023, Chao et al

    "It has been shown that innate immune responses can adopt adaptive properties such as memory. Whether T cells utilize innate immune signaling pathways to diversify their repertoire of effector functions is unknown. Gasdermin E (GSDME) is a membrane pore-forming molecule that has been shown to...
  4. Andy

    Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesis, 2021, Black et al

    Introduction Fungal pathogens threaten human health both directly as infectious agents and indirectly by limiting crop production, and new approaches are desperately needed to combat fungal diseases [1]. There is a growing appreciation that mitochondrial functions contribute to the ability of...
  5. Kalliope

    Autoimmunity Reviews: Dampness and mold hypersensitivity syndrome and vaccination as risk factors for CFS (Tamara Tuuminen et al - 2018)

    Not sure what this is. Couldn't find the article on Sci-Hub, but thought it was interesting with a CFS-study from Finland. One of the authors is Olli Polo, who has been involved with ME for a while. Dampness and mold hypersensitivity syndrome and vaccination as riske factors for chronic fatigue...
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