annesley

Real-Time Measurement of Mitochondrial Function and Glycolysis in Lymphoblastoid Cell Lines Katsaros, Tina; Missailidis, Daniel; Annesley, Sarah J. Cells require energy in the form of ATP to function. The two main ways in which cells generate energy in mammalian cells is through glycolysis and...

Mitochondrial Measures in Primary Cells Isolated from Patients with ME/CFS Allan, Claire Y.; Katsaros, Tina; Missailidis, Daniel; Fisher, Paul R.; Annesley, Sarah J. Fibroblasts and peripheral blood mononuclear cells (PBMCs) are commonly utilized cell types for the analysis of mitochondrial...

A blood-based mRNA signature distinguishes people with Long COVID from recovered individuals Missailidis, Daniel; Ebrahimie, Esmaeil; Mohammadi-Dehcheshmeh, Manijeh; Allan, Claire; Sanislav, Oana; Fisher, Paul Robert; Gras, Stephanie; Annesley, Sarah Jane Long COVID is a debilitating condition...

Cell invasive amyloid assemblies from SARS-CoV-2 peptides can form multiple polymorphs with varying neurotoxicity Oana Sanislav; Rina Tetaj; Metali; Julian Ratcliffe; William Phillips; Annaleise R. Klein; Ashish Sethi; Jiangtao Zhou; Raffaele Mezzenga; Sina S. Saxer; Mirren Charnley; Sarah J...

Abstract Neurological disorders, including neurodegenerative diseases, are collectively a major cause of death and disability worldwide. Whilst the underlying disease mechanisms remain elusive, altered mitochondrial function has been clearly implicated and is a key area of study in these...