amino acids

Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...

Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher & Christopher W. Armstrong Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and...

Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19 Chronic viral infections are ubiquitous in humans, with individuals harboring multiple latent viruses that can reactivate during acute illnesses. Recent...

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients Tsuge, Mitsuru; Ichihara, Eiki; Hasegawa, Kou; Kudo, Kenichiro; Tanimoto, Yasushi; Nouso, Kazuhiro; Oda, Naohiro; Mitsumune, Sho; Kimura, Goro; Yamada, Haruto...

Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST Hans-Georg Sprenger; Melanie J. Mittenbühler; Yizhi Sun; Jonathan G. Van Vranken; Sebastian Schindler; Abhilash Jayaraj; Sumeet A. Khetarpal; Ariana Vargas-Castillo; Anna M. Puszynska; Jessica...

Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach Sara Martínez; Oihane E. Albóniga; María Rosa López-Huertas; Ana Gradillas; Coral Barbas Despite the recent and increasing knowledge surrounding...

Metabolic Fingerprinting for the Diagnosis of Clinically Similar Long COVID and Fibromyalgia Using a Portable FT-MIR Spectroscopic Combined with Chemometrics Hackshaw, Kevin V.; Yao, Siyu; Bao, Haona; de Lamo Castellvi, Silvia; Aziz, Rija; Nuguri, Shreya Madhav; Yu, Lianbo; Osuna-Diaz, Michelle...

Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL Moon, Jee-Young;Chai, Jin Choul;Yu, Bing;Song, Rebecca J.;Chen, Guo-Chong;Graff, Mariaelisa;Daviglus, Martha L.;Chan, Queenie;Thyagarajan, Bharat;Castaneda, Sheila F.;Grove...

A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...

Significance Chronic fatigue syndrome is a multisystem disease that causes long-term pain and disability. It is difficult to diagnose because of its protean symptoms and the lack of a diagnostic laboratory test. We report that targeted, broad-spectrum metabolomics of plasma not only revealed a...

Hallmarks of Metabolic Reprogramming and Their Role in Viral Pathogenesis Allen CNS, Arjona SP, Santerre M, Sawaya BE Metabolic reprogramming is a hallmark of cancer and has proven to be critical in viral infections. Metabolic reprogramming provides the cell with energy and biomass for...

Hot off the press, just published today in Frontiers in Pharmacology. A group of researchers in China used metabolomics (measuring the concentration of many metabolism-related chemicals in the blood) to compare healthy controls with Covid-19 patients who were admitted to Jiaxing Hospital, but...

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227384

I wasn’t sure where to put this. It is general background information about metabolism, but since it is directly relevant to energy production in PWME and hence fatigue, I put it here. Recently I needed to refresh my memory about how some amino acids are broken down for energy. I thought I...