ALSUntangled 56: “ten red flags”-things to be wary of in alternative or off-label products
"Patients and families affected by disabling, life-shortening diseases such as amyotrophic lateral sclerosis (ALS) often turn to the Internet for answers (Citation1). There they can find a large number of...
Actively Protective Combinatorial Analysis: a Scalable Novel Method for Detecting Variants that Contribute to Reduced Disease Prevalence in High-Risk Individuals
Jason Sardell; Sayoni Das; Krystyna Taylor; Colin Stubberfield; Andy Malinowski; Mark Strivens; Steve Gardner
We present a novel...
"There are plenty of reasons to get off your duff and exercise—but is improving your brain one of them? The U.S. Centers for Disease Control and Prevention touts exercise as a way to “boost brain health,” while the World Health Organization suggests that about 2 hours of moderate activity or 75...
Abstract
Introduction
Fatigue is defined as a symptom of exhaustion unexplained by drug effects or psychiatric disorders and comprises two main components (i.e., central or “mental” and peripheral or “physical” components), both influencing global disability in amyotrophic lateral sclerosis...
The Centre Director for UK Dementia Research Institute at King’s was first to deliver a lecture as part of the 2022/23 IoPPN Inaugural Lecture Series.
lecture (32 mins) available at link...
I thought this was an interesting and hopeful article about the genetic basis for a well-known neurological disease and competing scientists actually working together...
Full title: Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes
Abstract
Background
Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease. ALS is determined by...
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