Search results

  1. J

    Intestinal interoceptive dysfunction drives age-associated cognitive decline 2026 Cox et al

    Ageing is accompanied by declining memory function, with extremely heterogeneous manifestation in the human population. Brain-extrinsic factors influencing cognitive decline, such as gastrointestinal signals, have emerged as attractive targets for peripheral interventions but the underlying...
  2. J

    Dr Ziyad Al-Aly

    Massive amounts of self-citations. I’ve pointed this out before about this guy.
  3. J

    Dysregulated NK-cell gene expression defines the enduring symptoms of long COVID-19, 2026, Ray et al

    Twitter is always true, isn’t it?
  4. J

    Preprint Spironolactone for ME/CFS in a Patient Homozygous for rs5522 (I180V): A Case Report, 2026, Donnellan et al

    Spiro brought up by Cort here (EBV) https://www.healthrising.org/blog/2020/08/12/spironolactone-epstein-barr-virus-chronic-fatigue-long-covid/
  5. J

    They feel bugs inside them. Doctors don’t know why—ME/CFS mentioned.

    But there are “bugs” like scabies that can infect you through your skin.
  6. J

    They feel bugs inside them. Doctors don’t know why—ME/CFS mentioned.

    Mentions ME/CFS. Komaroff is quoted. https://www.nytimes.com/2026/03/09/opinion/diagnosis-delusional-infestation-bugs.html?unlocked_article_code=1.R1A.eM89.0sDe0bJZYGVr&smid=url-share
  7. J

    Can a “Living Drug” Cure Autoimmune Diseases?

    https://www.newyorker.com/culture/annals-of-inquiry/can-a-living-drug-cure-autoimmune-diseases
  8. J

    A multi-omics recovery factor predicts long COVID in the IMPACC study, 2026, Gabernet et al.

    https://www.healthrising.org/blog/2026/03/05/blood-sex-inflammation-long-covid-chronic-fatigue/
  9. J

    Daratumumab, isatuximab (CD38 drugs)

    https://www.webmd.com/drugs/updates/fda-approves-uplinza
  10. J

    Genome modelling and design across all domains of life with Evo 2 2026 Brixi et al

    Not smart enough to understand this, but creating a lot of buzz right now.
  11. J

    Daratumumab, isatuximab (CD38 drugs)

    Did she say which CD19 targeting drug?
  12. J

    Genome modelling and design across all domains of life with Evo 2 2026 Brixi et al

    Genome modelling and design across all domains of life with Evo 2, 2026, Brixi et al Genome modelling and design across all domains of life with Evo 2 Abstract All of life encodes information with DNA. Although tools for genome sequencing, synthesis and editing have transformed biological...
  13. J

    Well-known, famous people with ME/CFS (public thread)

    I think they know he has ME/CFS but they don’t want to admit it. It’s easier to say he has POTS.
  14. J

    How do the various assays differentiate normal antibodies from autoantibodies?

    Ok same question tho—if you use HuProt, how do you tell normal Antibodies from autoantibodies?
  15. J

    "The Cost of Indifference: The sad and curious case of the chronic fatigue syndrome" (Quillette)

    Interesting….IIRC one of their writers (J. Kay) was sort of negative on long covid as a biological reality.
  16. J

    How do the various assays differentiate normal antibodies from autoantibodies?

    Please explain it like I’m 15. Thanks. How much error is associated with these assays? Assuming that there are autoantibodies associated with ME/CFS why have they been so difficult to find relative to SLE, RA, Sjogrens, scleroderma, etc?
  17. J

    Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting, 2020, Viola et al

    What does this mean?
  18. J

    Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting, 2020, Viola et al

    Abstract Daratumumab (Dara), a multiple myeloma (MM) therapy, is an antibody against the surface receptor CD38, which is expressed not only on plasma cells but also on NK cells and monocytes. Correlative data have highlighted the immune-modulatory role of Dara, despite the paradoxical...
  19. J

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    Not so much separation of the means. Looks like 225 versus 175 or so. Maybe no really low NK patients. But also larger sample size here—33 versus 10. But Fluge should have cited this in the Dara paper.
  20. J

    Well-known, famous people with ME/CFS (public thread)

    “Kerr indicated that the Warriors received internal confirmation before completing the trade that Porzingis was not dealing with POTS.” So why did they sign him?
Back
Top Bottom