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  1. rvallee

    Long COVID Treatment Guide (Patient-Led Research Collaborative & RTHM)

    I wouldn't necessarily fault this process if it found a very strong signal. When a formal process fails systematically, a distributed approach like this is sometimes the only viable way of working things out. It was just very unlikely to find anything. But it didn't. All of those signals are...
  2. rvallee

    Illness anxiety disorder and somatic symptom disorder: Similarities and differences in health-anxious individuals 2025 Newby et al

    Oh, do we have a new baby acronym? Never seen this one before. Ah, a quick search suggests this is a euphemism for hypochondria, because reasons, I guess. Because this is an industry that sees nothing wrong with putting a brick in a box and slapping a fake label on it so that people think they...
  3. rvallee

    Charting the circulating proteome in ME/CFS using cross-system profiling to uncover mechanistic insights, 2026, Hoel, Fluge, Mella+

    The fact that most LC cases stem from mild acute cases should have completely shut this nonsense down for good. In a sane world, it would have led to major changes. When you read back at the genesis of the ideology, it's all framed around this, around severe acute illness leaving people ill for...
  4. rvallee

    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    That question all on its own is absolutely damning, considering that the biopsychosocial model has been applied for about 3 decades. Completely inexcusable.
  5. rvallee

    Narratives of recovery from persistent fatigue: a stepwise learning process 2026 Linnros et al

    The 80s are calling. Works with either the 1880s or the 1980s. Literally the same narrative all over again. Literally. The same. Uh, so, not recovery, then? Even that would be a little too clownish for Orwell, who likely couldn't have conceived of physicians being so dishonorable. I will now...
  6. rvallee

    Treatment effects of multimodal inpatient psychotherapy for post-COVID patients: First results from a non-randomized, controlled study, 2026, Koller+

    This is especially problematic with clinical opinion being valid evidence in a court of law. If it can be as unreliable as this, this is far worse than even the main issue with most testimony in that people have unreliable memory. It's simply not credible for someone this involved not to know...
  7. rvallee

    Professor Michael Sharpe

    So, yeah, I took a look at the slides and... this is a sales pitch for something that you can imagine could work and how amazing it would be if it were actually true. It's like selling some amazing technology that could make any car do 100 km per litre and have 11/12 slides be all about how...
  8. rvallee

    Professor Michael Sharpe

    Technically, almost every single biopsychosocial trial qualifies as a pilot trial, in that they are small, methodologically awful, the results don't matter and they always call for more research. Also everything they do is novel and never-before-tried. So not so much "pilot everything" as...
  9. rvallee

    Professor Michael Sharpe

    "How it might work?" is not the kind of questions that should be current literally decades into mass implementation. All of this is speculative, when pressed on it everyone has to admit it, but they still find no problem forcing it onto millions and completely upending all medical based on the...
  10. rvallee

    Treatment effects of multimodal inpatient psychotherapy for post-COVID patients: First results from a non-randomized, controlled study, 2026, Koller+

    Uh, that's also not true. It's usually not the physical functioning that reports improvement, notwithstanding a couple of trials that may have randomly had that happen. It doesn't even make sense anyway, as CBT does not target physical functioning. Good grief why are we stuck with the weirdest...
  11. rvallee

    Norway: 2026 Guidelines for chronic fatigue and ME/CFS - draft published

    Most health care systems do have this right of refusal, though. I know for a fact we do here in Quebec. Doesn't mean professionals won't try to convince someone if they are making a dangerous choice. I doubt Norway is much different, and that this exemption is mainly for 'behavioral' issues...
  12. rvallee

    News from the USA, United States of America

    This some myth that needs to be busted hard. No, it isn't. There is absolutely nothing that requires it to be, it's just the natural course for a lot of people but it doesn't mean we can't change that. Most who recover do so relatively quickly, and there have been some rapid sudden recoveries...
  13. rvallee

    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    I usually just call this lying, but I'm a weirdo who values integrity so there's that.
  14. rvallee

    Preprint A phase 2a double-blind, placebo-controlled randomized trial of the SARS-CoV-2-specific monoclonal antibody AER002…, 2026, Peluso+

    Uh, no. There were no differences, therefore there was no 'response', in either arm, which means this is a natural process. This is exactly what is expected from a treatment that doesn't work, it should be no different than a null control. That's the whole point of a comparison trial! What is...
  15. rvallee

    The association between hair cortisol levels, Epstein-Barr virus infections and chronic fatigue in adolescents, 2026, Kongsnes, Wyller et al

    This bothers me because I noticed it at first but assumed I must have missed something and didn't bother digging further. But this is the only plausible explanation. This claim keeps being repeated as a fact. No doubt Wyller and his colleagues will not have stopped saying it, and won't even stop...
  16. rvallee

    The association between hair cortisol levels, Epstein-Barr virus infections and chronic fatigue in adolescents, 2026, Kongsnes, Wyller et al

    Likely more of a case of Sinclair's "It is difficult to get a man to understand something, when his salary depends on his not understanding it". It's a bit more complex in that they their lives, and salary, would be largely identical if they had spent their career doing anything else, but they...
  17. rvallee

    Opinion Is the RACGP HANDI recommendation of incremental physical activity for CFS/ME harming patients?, 2026, Stallard/Praet/Gupta/Smith

    Something I just realized. As is tradition, HANDI responded with some whine about NICE's evaluation process being 'controversial' and flawed. Even though most of the psychobehavioral proponents implicitly agree with that evaluation, they just can't deal with how it exposed how most of what they...
  18. rvallee

    Norway: 2026 Guidelines for chronic fatigue and ME/CFS - draft published

    I pretty much universally find that this whole idea only makes sense when we substitute fatigue with motivation. Everything fits into place when that's taken into account. So, for most deniers, we might as well have "chronic low motivation", not even a need for syndrome. Therapy then becomes...
  19. rvallee

    Prevalence of Multiple Chemical Sensitivity in Canada Between 2000 and 2020, 2026, Robins et al

    Sadly, I don't think the % of physicians who don't recognize the problems that MCS describes is much different than for ME/CFS. In fact, they might be close to identical (with emphasis on ME/CFS, not mild generic chronic fatigue). However much progress has been made on the research front, even...
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