Search results for query: migraine

Recent article about ubrogepant for migraine prodromal symptoms (link to thread): Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial (2025, Nature Medicine)

Nature News: 'Migraine drug is first to tackle debilitating early symptoms' [Paywall] "Scientists have shown that a drug approved to treat migraine headaches can also alleviate debilitating non-headache symptoms, such as fatigue, brain fog and blinding light sensitivity, that occur as the...

Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial Peter J. Goadsby, Jessica Ailani, David W. Dodick, Amaal J. Starling, Chengcheng Liu, Yingyi Liu, Sung Yun Yu, Jonathan H. Smith, Elimor Brand-Schieber & Joel M...

I don't know—I have the same thing with almost the same timings. But it's interesting, and possibly unusual enough to be useful in a treatment trial. Not everyone has this kind of reversal, but for those who do it might serve as a marker of improvement after treatment. I'm only making a note...

Do we know why we get reverse sleeping? My pattern is sleep 4/5am through to 12/1pm it does change about at times (such as if I get a migraine and sleep all day, or am woken up a lot and go to bed early rather than nap). So my sleep has reversed, fine, I can cope with that, I made myself so...

That’s really interesting, have you or any of your family members done whole genome sequencing? It would probably be a crap shoot if you don’t have a good geneticist that could interpret a result that’s not already well associated with a disease, but could turn up something useful.

...is of my direct “ancestors”, (people who contributed genetically to me), its only the women who had autoimmune/autoinflammatory/(ME/CFS, Migraine like illnesses). Literally only the women. It’s my mum’s family. My mum’s mum’s family, and my mum’s mum’s mum’s family. (I’m a man tho and the...

I keep coming back to a “perfect storm” idea of ME/CFS—there could be a wide variety of genetic predispositions which don’t guarantee ME/CFS but make you a lot more likely to develop it if you also have the right combination of environmental triggers. You just keep stacking cards towards one...

...really does resonate with me though. My mum has an ME/CFS like chronic illness that looks similar to mine when I was really mild (she gets a migraine and has to lay in bed for days after she does too much) although she was diagnosed with hEDS (after lots of "depression" and "burnout" type...

...for that matter. Other meds knocked me out, but did not subjectively improve my perceived sleep quality or gave me nasty side effects like migraines. Besides countless supplements from minerals to amino acids to herbal extracts, I have tried H1-antagonists/inverse agonists (promethazine...

...Program Armand Gerstenberger, Niloofar Afari, Marianna Gasperi [Line breaks added] Chronic overlapping pain conditions (COPCs) include migraine, tension headache, irritable bowel syndrome, chronic back pain, fibromyalgia, chronic fatigue syndrome, and chronic prostatitis. Environmental...

they don’t even need to misremember or confuse it. If my doctor diagnoses me with migraines and a survey asks me if I’ve been diagnosed with “Migraine syndrome”, the reflex of pretty much anyone who isn’t super informed or pedantic will be to say yes. I mean you’ll just assume their the same...

...Saw the name “chronic fatigue syndrome” a coupe times. Was like — nope, that’s not my problem. My proboem is whenever I exercise I get a migraine, feel sick, and my stomach hurts for the next couple days. This is actually how I mostly experience PEM. More this than the sort of small...

Scientists pinpoint cause of migraines - paves way for new treatment

...control after covid-19 infection is an increase in scoring above the threshold to be given an ADHD diagnosis. To me, the triggers for child migraines (smell and light especially, but also physical activity) and the initial pain, that wasn't always "pain" but felt very tiring, when being...

This popped up in my google scholar alerts too, due to the mention of ME/CFS, which from their definition I’m not convinced the author understands particularly well. I don’t think they're trying to dismiss it, just don’t understand it. There’s acknowledgment of people not being believed etc...