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Abstract Inflammatory bowel disease (IBD) is a complex chronic inflammatory disorder of the gastrointestinal tract. Extracellular adenosine triphosphate (eATP) produced by the commensal microbiota and host cells activates purinergic signaling, promoting intestinal inflammation and pathology...

Perhaps we should add a new emoji for the PG thread from banging our heads?

I had a sudden viral onset, and whatever was occurring in my immune system during that time period seems to have activated h pylori infection. I might have been asymptomatic w h pylori for years, but the viral onset altered my immune system and brought it to surface. Just a theory of...

Ditto. I have fever blisters on my tongue and lips this week. I've also been having fluid buildup in my right ear and sinuses, and it's not allergy related. When I hold my nose to try to deblock, I hear this load sweak coming from my R ear.

My n=1 suspicion. It's possible that I contracted Covid early last year before the WHO declared the pandemic. I've mentioned my vestibular virus several times here so not going to bore everyone, but I'm still dealing with it over one year later. I have never experienced this type of...

There were several doctors in Canada that had their lives threatened b/c they promoted vaccines on social media. Some perps showed up at their homes.

What? "At the centre they are tested for signs of long-term organ damage and taught how to overcome the key symptoms - shortness of breath, fatigue, low mood and "brain fog"

Third dose data in solid organ transplants, now from France. Antibody response up from 40% (2 doses) to 68% (3rd dose) And Ab levels go up in all. https://www.nejm.org/doi/full/10.1056/NEJMc2108861

People want to feel like they're in control, and pushing themselves gives them a feeling of accomplishment. I pushed myself in the earlier years of ME, but it didn't turn out so well.

It's a very small percentage, and even though children may experience frequent attacks (possibly more than typically seen in adults), studies have shown that children also seem to have very good recovery that is often more rapid than adults

Wow, I talked about ME for 7 years straight to anyone who would listen, and then realized no one was interested so I stopped.

I felt pretty much recovered after 9 months of PVFS and returned to work. My equilibrium and sleep was the first sign that something was wrong after only 10 days. I wasn't fatigued or sick, it felt like a switch had turned off.

And there's also remitting-relapsing episodes that occurs with PVFS and ME. I rested very well for the first 7 years and reached a level of 80-90% improvement. I don't believe resting for another 5 years would have made any difference in my situation. When we start exerting ourselves...

My experience with having ME for 30 years and interacting with pwME, is that some of us develop comorbidities over time that will determine the progression of the illness, spontaneous recovery isn't dependent on resting early in my experience, but does prevent PEM from becoming worse. Some...

I forgot to mention that the mag shots were injected in my butt :laugh: Either way, I always thought it would hit bone .

I used 38mm needles when I injected IM with magnesium sulfate and I'm slim. I think they should use this size for all IM injections.

I wasn't surprised to learn recently that POTS is now being referred to as 'deconditioning' too :emoji_rolling_eyes: The Dysautonomia folks posted a recent tweet highlighting an Olympic swimmer dx with POTS as not having 'deconditioning'.

My sister gets dizziness from time to time from Hashimoto and has to take a day off work. She gets fatigue but can still work, but high impact aerobic exercise is hard for her. She experiences what she describes as 'brain fog', which is not at all close to what I experience with...

His behaviour is insulting and irresponsible, and does not reflect the experiences of pwME by making comments such as 'disarming'' ME/CFS. His dismissiveness towards pwME when they tried to explain their experiences says a lot about him.

This article was going well until . . . PG is making his 'mark', as you say n=1 everywhere. It's truly baffling. https://www.discovermagazine.com/health/what-we-know-and-dont-know-about-long-covid What bothers me more is that CFS (or ME) is linked to his name.