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Just a little quibble - there seems to be a suggestion, especially in the summary article, that the services and interventions have worked for a small number of patients. We don't have any evidence of that - improvements could have been the result of cold-water bathing or stomach massage or...

I'm looking forward to reading this paper. I agree with others that this is a really interesting approach (also agree with the gender gap comment :(). I wonder how many countries would have similarly strong and linked databases of medical records and income information available to...

I suspect that there might have been some bias in the demographics of the studies. I think it is less likely that the frail elderly and the very sick (people with high blood pressure that is rather resistant to improvement created by exercise) would have been signing up to do planking and wall...

This is an interesting paper, especially with the corroboration of the reduced ETS1 finding. Google AI said: The transcription factor Ets1 is is highly expressed in B cells, particularly in naive B cells, and plays a key role in regulating B cell development and function: Expression Ets1...

I doubt that it was the primary outcome scale that was the major problem here, causing the people who own the BC-007 intellectual property to pack up and go home. If patients were reporting miraculous recoveries in everything except fatigue, I'm sure they would tweak their experimental design...

That's not a very impressive improvement over the 6 months, considering natural improvement. And that the people who dropped out may have been too sick or too disillusioned to turn up to the follow-up.

From the article: That may be useful for people advocating for children to get access to vaccinations. (although I think the protection provided by vaccination is over-stated, as is the protection provided by not being obese).

Jeanne Marrazzo - Director of the National Institute of Allergy and Infectious diseases, NIH Gary Gibbons - Director of the National Heart, lung, and Blood institute Walter Koroshetz - Director of the National Institute of Neurological Disorders and Stroke

Ditto for people with a similar condition to mine, given that pilates is all about strengthening the core. Analysing what they say there in the abstract: Case series study = no controls, so we have no idea if people would have had reduced fatigue levels at the end of the period regardless of...

Ah, that will be the youth-giving effects of the Perrin technique.

I really feel your pain @Yann04. So much research is rubbish. Just yesterday, I listened to a young researcher on the radio. The interview was billed as 'why mindfulness or gratitude journalling may not be the way to happiness - the problems with research on happiness'. "Great!" I thought...

For sure, but there are things that can be done to make more homogeneous cohorts e.g. people whose collection of symptoms meet ME/CFS criteria and who have had the symptoms for over one year; people with observable lung damage; people who were on mechanical ventilation and have observable lung...

From another study: Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection, Matthews et al, 2024 It also found increased PD-1 and TIM3 expression (but higher rather than lower specific antibody levels) in the Long Covid group. It looks...

That is looking pretty good. Quotes from the survey: I thought that was interesting, because, it is true that for psychological services aimed at helping people cope, what matters is how the patient feels rather than the level of activity. Of course though, that could be seen to exempt...

Tom Kindlon tweeted this: And, it really is great. Yes, going just by the abstract, a helpful paper with a sufficient sample size. I take this as more evidence that cortisol is not relevant to ME/CFS. The levels were not even trending to lower. Indeed. It's a shame that that point was not...

It's been a while since I actively used LinkedIn but I think it is getting more popular for posting information with the decline in Twitter/X. I wonder, how many of our members have a LinkedIn account and how many of you actively use it? Can you tell us about any experiences using LinkedIn...

Barriers and facilitators of healthcare access for LC patients in a universal healthcare system: qualitative evidence from Austria, 2024, Gamillscheg

I'm trying to think of the confounding factors, just for something to do - maybe a change in access to diagnosis? Maybe people couldn't get to the doctor during the first part of the pandemic, and then there was a backlog to get to specialists so as to get diagnosed with these conditions. So...

That said, I note: