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  1. Midnattsol

    Pain in adolescent chronic fatigue following Epstein-Barr virus infection, 2020, Wyller et al

    As with the CBT study, participants wore acceleromaters for a week. The chronic fatigue positive group had a daily mean of 8710 with an SD of 3872, while the chronic fatigue negative group had a daily average of 9329 with an SD of 3019. They don't write how PEM is measured (I guess the same way...
  2. Midnattsol

    Healthcare workers during corona want better work conditions, not psychological help

    A bit related to the pyschologization of symptoms in disease. Health care workers during the pandemic have been offered to talk to psychologist, but most actually wanted better work conditions (data collected between january and april, mostly in China)...
  3. Midnattsol

    CBT combined with music therapy for chronic fatigue following Epstein-Barr virus infection in adolescents: a feasibility study, 2020, Wyller et al

    If there's more follow up posts on this, they have published results separately on the music therapy part, where it is stated that the music therapy was part of a randomized controlled trial (my bold). http://mmd.iammonline.com/index.php/musmed/article/view/679
  4. Midnattsol

    BPS attempts at psychologizing Long Covid

    The more people he asks if they are saying they don't believe in psychological illness, the more I hope it become clear that BPS defenders are one trick ponies. Ok two tricks, the BPS approach itself and the "opponents are afraid of the stigma of mental illness" deflection.
  5. Midnattsol

    Signs of Intracranial Hypertension, Hypermobility and Craniocervical Obstructions in patients with ME/CFS (Pre-print 2019/published 2020) Bragée et al

    I'm not sure I see the discrepancy, I have had symptoms for 10 years soon, but was only diagnosed three years ago.
  6. Midnattsol

    The Low Glutamate Diet Effectively Improves Pain and Other Symptoms of Gulf War Illness, 2020, Baraniuk

    Welcome to the world of nutritional science :( Re fluctuating symptoms - you can have fluctuating levels of the metabolites that are causing problems I guess.
  7. Midnattsol

    The Low Glutamate Diet Effectively Improves Pain and Other Symptoms of Gulf War Illness, 2020, Baraniuk

    But the question is - do you have to remove food that naturally contains glutamate? Some of the foods listed in this thread are associated with inflammation for other reasons than their glutamate content (I get symptoms if I eat nightshades). Other dietary approaches that change your metabolism...
  8. Midnattsol

    The Low Glutamate Diet Effectively Improves Pain and Other Symptoms of Gulf War Illness, 2020, Baraniuk

    Hasn't this been discussed in another thread? Or was that a low glutamate diet for fibromyalgia? Anyhow, if their "low glutamate diet" is like the other low glutamate diet and actually a "low preprocessed food with added MSG diet" it's misleading. Glutamate levels can be affected by other...
  9. Midnattsol

    Open Medicine Foundation (OMF)

    Exciting :) I feel better after several days of sunny (not too hot!) weather and have been thinking about NO metabolism, blood vessels, mitochondria etc.
  10. Midnattsol

    Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome, 2020, Miura et al

    They state that the relationship between VDR and Claudin-2 is controversal because it is decreased in the intestine of VDR knockouts but increased in the intestine of VDR knockouts exposed to dextran sodium sulfate? That's two very different states, one with an irritant to the epithelium and one...
  11. Midnattsol

    Investigating subjective experiences of cognitive difficulties and objective measures of cognitive functioning in adolescents who had EBV, 2020, Rødø

    Since it's part of CEBA I'm not surprised they went with the sustained arousal model. :/ I do wonder when they (CEBA project, not this particular thesis) decided to look at both CF and CFS. In the music study they include patients with CF who "if having additional symptoms" could also be...
  12. Midnattsol

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    PCA is an unsupervised method so does not try to separate between samples and controls, that's why getting separation at all is considered good/useful. The variance is frustrating to me as I've gotten as many different explanations for how much I should care about it as I've had teachers. I've...
  13. Midnattsol

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    The "goal" of PCA is not to get separation on the x or y axis, you just want separation. And they do get separation here, even if the patients are not in a nice cluster (Although to me P1 and P7 could have been left with the controls). However, if they only have very few samples/participants and...
  14. Midnattsol

    Discriminatory cytokine profiles predict muscle function, fatigue and cognitive function in patients with ME/CFS. McArdle et al. 2020

    It was mean corpusclar volume I was thinking of and I'm pretty sure I would have picked that up if it was "common" :P I misread as you assumed :)
  15. Midnattsol

    Discriminatory cytokine profiles predict muscle function, fatigue and cognitive function in patients with ME/CFS. McArdle et al. 2020

    I did not know that MCV was different between pwME and healthy controls. Anyone know more about this?
  16. Midnattsol

    Validation of the Severity of ME/CFS by Other Measures than History: Activity Bracelet, CPET, SF-36. van Campen et al, 2020

    I also average 8000 a day, with min-max being ~800 and ~14000 last three months if I remember correctly. 8000 is the mean in my follicle phase (right after menses), and ~5000 in my luteal phase (after ovulation). My min step count the previous three months has been ~2000 in the follicle phase...
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