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Abstract Background Diminished muscle protein synthesis in cirrhosis leads to reduced strength and mass, impacting daily activities and overall quality of life. Aims This study aimed to examine the effectiveness of exercise intervention in body composition, exercise capacity, fatigue, and...

Yep, my functional level is even lower and the demands on my time are even higher.

All major ME/CFS criteria include immediate exacerbation of symptoms in their descriptions of PEM - that is the most serious problem.

Todd Davenport, of the Workwell Foundation, was asked if the 2xCPET measured PEM or the associated energy loss. The start of his answer is "Thanks for this interesting question and set of observations. I appreciate you sharing them, as I also appreciate the chance to share. In the first part...

"Funding This study is funded by the NIHR Health Services and Delivery Research programme (project: 15/136/07)." Googling that project reference leads me to the Multiple Symptoms Study 3 page on the Uni of Sheffield website, https://www.sheffield.ac.uk/ctru/current-trials/mss3, and reminded me...

"Influenza is the pathogen most likely to trigger a new pandemic in the near future, according to leading scientists. An international survey, to be published next weekend, will reveal that 57% of senior disease experts now think that a strain of flu virus will be the cause of the next global...

USDA Confirms Cow-to-Cow Transmission a Factor in Avian Flu Spread "The U.S. Department of Agriculture said this week that cow-to-cow transmission is a factor in the spread of avian flu in dairy herds, but it still does not know exactly how the virus is being moved around. Farmers and...

For clarity, I doubt that viral persistence is the issue for folks with Long Covid, or for that matter ME/CFS. However, I would be happy to change my mind if presented with a decent evidence base to support it. But I am all for patient groups forcing policy makers to abandon hypotheses that...

"Friday 19th April 2024 marked the inaugural meeting of the PANS PANDAS Clinical Guidelines Development Group, held in central London. With 30 attendees, including clinicians from all relevant fields of medicine and representatives from the patient community, the formation of this group...

Three likes, four re-posts.

Published papers thread for w/c 15th April. Facebook: https://www.facebook.com/sci4me/posts/pfbid02zGkW2E1kNnAxvR6a21cdPyvcHRoXwmztk76rbahvcDe6meJHA3FtxpcYv5EUnkTfl Mastodon: https://med-mastodon.com/@s4me/112314128676593530

Yes, of course others can. I have no available capacity to start a S4ME social media campaign.

Previously posted: Social media posts linking to the two letters sent by the committee. Facebook: https://www.facebook.com/sci4me/posts/pfbid0cUCd2zbtnYTLtLFB6YwCYk3YHh1cjgsNUByaos5WvvCfDFmXHszGDnU3hnX6GkFXl Mastodon: https://med-mastodon.com/@s4me/112252304846115728

Article: My insomnia hell: sleeplessness is a curse – but I think I finally have the answer [not ME/CFS related but familiar 'cures' that didn't] https://www.theguardian.com/lifeandstyle/2024/apr/21/my-insomnia-hell-sleeplessness-is-a-curse-but-i-think-i-finally-have-the-answer

Trial By Error: A New Study from Exeter on “Brain Training” for Treatment of Post-Covid Cognitive Problems https://virology.ws/2024/04/10/trial-by-error-a-new-study-from-exeter-on-brain-training-for-treatment-of-post-covid-cognitive-problems/

Except when certain hypotheses cause harms that are widely reported by the majority of patients surveyed. That is when it is appropriate to be against those.

"The primary outcome will be cognition measured by the FLAME computerised cognitive test battery, with secondary outcomes of cognition, function, fatigue, mood and quality of life. Service use and employment will be collected to support a health economics analysis. Analysis will follow an...

Preprint Psychobiological regulation of plasma and saliva GDF15 dynamics in health and mitochondrial diseases Abstract GDF15 (growth differentiation factor 15) is a marker of cellular energetic stress linked to physical-mental illness, aging, and mortality. However, questions remain about its...

News in Brief posts for w/c 15th April. Facebook: https://www.facebook.com/sci4me/posts/pfbid02MTh5tN2VESivezn4QPQvHSfitgHHaRKHjooR882TLm29PQu9oKDCXagzzDhPhun3l Mastodon: https://med-mastodon.com/@s4me/112308490321239132

A general thread meant for interviews, articles and such like. Video podcast with Dr Speight, "Post-Exertional Mayonnaise: Myalgic Encephalomyelitis and a history of disbelief with Dr Nigel Speight",