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  1. Andy

    Guide: Involving People with ME and Other Energy Limiting Conditions, by the World ME Alliance

    I've posted before reading this, so have no opinion on it yet, although at the least I think the topic is an important one.
  2. Andy

    Guide: Involving People with ME and Other Energy Limiting Conditions, by the World ME Alliance

    The World ME Alliance, a global coalition of organisations advocating for those affected by Myalgic Encephalomyelitis (ME), is proud to announce the release of a new guide. This comprehensive resource, titled “Involving People with ME and Other Energy Limiting Conditions,” aims to promote...
  3. Andy

    UK: New £14 million investment targets rare diseases

    A new platform bringing together UK strengths in rare diseases research to improve diagnosis and treatment through better understanding of the disease. The UK Rare Disease Research Platform has been established with a £14 million investment over five years by the Medical Research Council (MRC)...
  4. Andy

    The neuroimaging evidence of brain abnormalities in functional movement disorders, 2021, Sasikumar and Strafella

    So when properly investigated physical abnormalities are found in people diagnosed with a functional condition, and somehow that supports the idea of functional conditions, rather than highlighting how flawed it is?
  5. Andy

    Closed UK: DecodeME updates, was recruitment thread.

    In the UK there is, https://bepartofresearch.nihr.ac.uk/, but awareness of it is low.
  6. Andy

    Typing myalgic encephalomyelitis by infection at onset: A DecodeME study, 2023, Bretherick et al

    Revised version is available, following peer reviewers comments, https://openresearch.nihr.ac.uk/articles/3-20/v2 "Amendments from Version 1 The revised manuscript has benefited greatly from the reviewers’ constructive suggestions. In response, the study’s main aim has been made explicit in...
  7. Andy

    Functional Neurological Disorder (FND) - articles, social media and discussion

    Jon Stone has had an editorial published titled "Functional neurological disorder: Past, present and future", paywalled, https://www.sciencedirect.com/science/article/abs/pii/S0013700623000908, with no abstract available. What is shown is "Acknowledgments This special FND issue of L'Encéphale...
  8. Andy

    Review Mechanisms and Severity of Exercise Intolerance Following COVID-19 and Similar Viral Infections: A Comparative Review 2023 Weldon et al

    What a mess of an article. Just two examples "Post-Infection Fatigue Syndrome (PIFS) As discussed above, there is an acute decrease in strength and endurance immediately following a febrile illness. However, in some patients, symptoms may persist and result in chronic exercise intolerance and...
  9. Andy

    Review Mechanisms and Severity of Exercise Intolerance Following COVID-19 and Similar Viral Infections: A Comparative Review 2023 Weldon et al

    Abstract Approximately 19% of the population is suffering from “Long COVID”, also known as post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC), which often results in exercise intolerance. As COVID infections continue to be common, studying the long-term...
  10. Andy

    Functional Neurological Disorder (FND) - articles, social media and discussion

    Trial By Error: A Letter to Psychological Medicine about Inflated FND Rate Claims "The journal NeuroImage: Clinical, an Elsevier title, recently agreed to correct the false statement that a 2010 study found functional neurological disorder to be the second-most-common diagnosis at outpatient...
  11. Andy

    First major survey of doctors with Long Covid reveals debilitating impact on health, life and work, 2023, BMA media team

    And that is from people who are part of the system. And from the report, "It has been informed by a UK survey of over 600 doctors suffering from the continuing effects of an infection with COVID-19, as well as wider research of the issues. The survey was undertaken by the BMA in partnership...
  12. Andy

    Wearable movement-tracking data identify Parkinson’s disease years before clinical diagnosis 2023 Schalkamp et al

    Parkinson’s disease is a progressive neurodegenerative movement disorder with a long latent phase and currently no disease-modifying treatments. Reliable predictive biomarkers that could transform efforts to develop neuroprotective treatments remain to be identified. Using UK Biobank, we...
  13. Andy

    Letter: The overview on current evidence for the treatment of ME/CFS is based on the principles of scientific assessment 2023 Ludwig et al

    Blog from Brian Hughes. “A science that does not allow opposing opinions abolishes knowledge.” Er, kind of "Colleagues and I have responded to a paper in Der Nervenarzt, the leading German neurology journal, pointing out various reasons why its “overview” of evidence-based approaches to ME/CFS...
  14. Andy

    YourgutPlus+ - a pro- and pre-biotic supplement

    From their FAQ, https://yourgutplus.com/frequenty-asked-questions/ 1. What is a delayed release capsule? The vegetable based capsule which carries the ingredients is designed to resist the acid in the stomach allowing the healthy bacteria to pass into the remaining gut where they are most...
  15. Andy

    The Intriguing Role of Histamine in Exercise Responses, 2017, Luttrell

    One of our oldest threads discusses this, Ranitidine (Zantac) for its IL6 inhibitory properties
  16. Andy

    The Intriguing Role of Histamine in Exercise Responses, 2017, Luttrell

    Not surprising, some people with ME/CFS have reported benefit from them as well.
  17. Andy

    Distinctive cancer-causing variant found in families from Orkney

    Have you not read the article linked in the following post?
  18. Andy

    Review Understanding functional neurological disorders: From biological markers to pathophysiological models, 2023, Conejero et al

    Functional neurological disorders have witnessed intense research activity in the fields of structural and functional neuroimaging for more than twenty years. Thus, we propose a synthesis of recent research findings and etiological hypotheses that have been proposed so far. This work should help...
  19. Andy

    Review Antimicrobial therapies for chronic pain (part 2): the prevention and treatment of chronic pain, 2023, Wang et al

    Abstract The discovery and development of antimicrobial therapies represents one of the most significant advancements in modern medicine. Although the primary therapeutic intent of antimicrobials is to eliminate their target pathogens, several antimicrobials have been shown to provide analgesia...
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