Step 1 - define area of interest
Step 2 - conduct a literature review to enable you to either build on previous findings/ explore a " gap" in knowledge
From undergraduate stats lectures- first lecture. I take it the literature review was as all encompassing as the above result would suggest...
Are actometers worn all the time? From a previous thread relative to paediatric EC studies i seem to remember that their use was intermittent ( could be wrong) . In which case what is being measured is a key question.
The link to activity and misdiagnosis is interesting and may be another...
I agree, but virtually impossible to get anyone to consider this. I' ve given up with my GP and no private providers do any other investigative processes anywhere near us. I am hoping that this gets further study.
A couple of queries
Is this the proposed study whose reviewers savaged it and was likely never to be published?
Is this a means of not providing data that can be analysed by others ?
Similar to @BeautifulDay ' s theory that some genetic mutations create a predisposition .
Link to PR thread where there are some slides
https://forums.phoenixrising.me/index.php?threads/video-mutations-in-energy-and-autoimmune-genes-cooperate-to-cause-me-cfs-with-alan-light-phd.62439/#post-1016900
I am probably being incredibly stupid, not having much biochemistry, but to me small differences are not the issue. Given the common nature of expression , surely in a system s condition it is not the individual difference s, but the cumulative effect of them that is as important?
How do these...
Note semi structured interviews - the framing of the topic would be interesting to see and may account for the fatigue focus and any introduction of bias; is there any way to access this ?
I find it disheartening that after so many years of adolescent research, that researchers and those treating the illness have not got to grips with the basics.
It is not fatigue, it is fatiguability that distinguishes things; moreover fatigue may not be the most debilitating of symptoms for...
New paper - has a number of red flags.
Focuses on fatigue description and " payback" as a description for PEM without much definition. Questionnaire based, pre diagnosed
Mild/ moderate but not housebound
I don't know if any comorbidities (OI, EDS etc) have even been thought about
I have not...
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