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Abstract Objectives Uncertainty regarding the legitimacy of functional neurological disorder (FND) remains among some health care professionals. Despite treatment guidelines and consensus recommendations, variability in clinical practice referral decisions persists. Evidence from other...

ABSTRACT Post-viral syndrome is a well-known medical condition characterized by different levels of physical, cognitive, and emotional impairment that may persist with fluctuating severity after recovering from an acute viral infection. Unsurprisingly, COVID-19 may also be accompanied by...

"On 6 December 2022, the European Commission approved the second work program of Horizon Europe for the years 2023-2024. In this article, we highlight several grants that may be relevant for scientists studying myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)."...

The European ME Coalition have published an explainer of the grants that can be applied for, thread here, Blog: European ME Coalition: Horizon Europe calls 2023-2024

You mean a MOA? ;)

Study Reveals Mechanism Involved in Neuropathic Pain and Could Help Develop Specific Treatment "Summary: Study reveals the role played by neuropathic pain in dendritic cells in the meninges via an increase in the metabolic kynurenine pathway. When the kynurenine pathway initiated by IDO1 was...

Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological mechanisms involved in neuropathic pain development are poorly understood. In this study, we found that neuropathic pain is abrogated when...

Eight (or more) logical fallacies in that paper bemoaning the new NICE guideline for ME/CFS https://thesciencebit.net/2023/01/10/eight-or-more-logical-fallacies-in-that-paper-bemoaning-the-new-nice-guideline-for-me-cfs/

Background: Irritable bowel syndrome (IBS) is a chronic disabling condition without a well-defined etiology. Infectious gastroenteritis (IGE) has been linked to this syndrome. There are few data from Iran on this association. Methods: In August 2018, an epidemic of IGE caused by Escherichia...

Highlights • High approach is associated with lower probability for having multiple symptoms. • while high resignation and diversion is associated with higher probability. • Exclusion of respondents with chronic disease did not alter the main results. • Coping could be important for prevention...

ABSTRACT Background Functional Gait Disorders (FGD) are a common presentation of motor-Functional Neurological Disorders (motor-FND) that affect walking ability. Aim To provide a narrative review of the current literature on FGD. Methods A narrative overview of published literature was...

Many patients infected with SARS-CoV-2 report persistent symptoms that may impair their quality of life for months, even after a mild episode of coronavirus disease 2019 (COVID-19), a situation often referred to as ‘long COVID’. Figures vary between studies but the proportion of patients...

Background Non-clinical evidence and a few human studies with short follow-ups suggest increased risk of dyslipidaemia in the post-acute phase of COVID-19 (ie, >30 days after SARS-CoV-2 infection). However, detailed large-scale controlled studies with longer follow-ups and in-depth assessment of...

Abstract OBJECTIVES: Fibromyalgia is a prevalent disease of unknown aetiology and is difficult to diagnose. Despite the availability of the American College of Rheumatology criteria for diagnosis, it continues to be a challenge in the field of primary health care in terms of identifying...

"Even though the US Centers for Disease Control and Prevention in Atlanta is the country’s leading public health agency, other government entities are not always up-to-speed on the latest recommendations. That could explain why the Department of Veterans Affairs appears to be using a variation...

3. We suggest offering cognitive-behavioral therapy for CMI and symptoms consistent with fibromyalgia, irritable bowel syndrome, or myalgic encephalomyelitis/chronic fatigue syndrome. 4. We suggest offering mindfulness-based therapies for patients with CMI and symptoms consistent with...

"There is neither a unique International Classification of Diseases, Tenth Revision code for CMI nor a universally accepted clinical case definition and standardized terminology for CMI. The Institute of Medicine5 ,6 (now the National Academy of Medicine) recognizes 2 case definitions for...

"Chronic multisymptom illness (CMI) is a condition characterized by multiple poorly understood symptoms not better accounted for by other behavioral or physical health conditions. For military personnel deployed during the Gulf War (1990-1991), CMI, termed Gulf War illness in this cohort, was...

Full title: Management of Chronic Multisymptom Illness: Synopsis of the 2021 US Department of Veterans Affairs and US Department of Defense Clinical Practice Guideline Abstract In 2019, senior leaders within the US Department of Veterans Affairs and the US Department of Defense commissioned the...

Copying this here in case anybody would be happy to be interviewed by Mike.