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  1. Andy

    Preprint: Disease diagnostics using machine learning of immune receptors 2023 Zaslavsky et al

    Abstract Clinical diagnoses rely on a wide variety of laboratory tests and imaging studies, interpreted alongside physical examination findings and the patient's history and symptoms. Currently, the tools of diagnosis make limited use of the immune system's internal record of specific disease...
  2. Andy

    Closed UK: DecodeME updates, was recruitment thread.

    We obviously hope it is still possible to hit our target but we only have funding for a set period, so there may come a point where we have to close recruitment to allow for analysis of all of the samples that we do have. We are grateful to everybody who has already shared details of the study...
  3. Andy

    USA: NIH National Institutes of Health news - latest ME/CFS webinar 14 Jan 2025

    From an NIH email. NIH ME/CFS Newsletter, Feb 2023 "This newsletter provides updates and information about new and ongoing activities at the NIH related to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)." See attached file. I don't think there is anything in it that hasn't been...
  4. Andy

    Closed UK: DecodeME updates, was recruitment thread.

    A new blog/email newsletter. What We Achieved in 2022 "As we resume work for the year ahead, we want to take the opportunity to look back on 2022 and see all we have achieved so far in this study. Summary: We opened phase 1 to a few hundred paper participants in January. Their feedback led...
  5. Andy

    EU: News from the European ME Coalition (EMEC)

    The scoping study has finally been published "The long-awaited scoping study has finally been published. This document defines “high-burden under-researched medical conditions” that will be targeted in future calls of the Horizon Europe research program. ME/CFS made the list but so did a lot of...
  6. Andy

    Preprint: Localized cardiac metabolic trajectories and post-infectious metabolic sequelae in experimental Chagas disease 2023 Liu et al

    Post-infectious conditions, where clinical symptoms fail to resolve even after pathogen clearance, present major health burdens. However, the mechanisms involved remain poorly understood. In Chagas disease (CD), caused by the parasite Trypanosoma cruzi, antiparasitic agents can clear T. cruzi...
  7. Andy

    Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and... 2023 Rodrigues et al

    Full title: Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling Introduction: The development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte...
  8. Andy

    Adolescents with functional somatic syndromes: Symptom profiles, illness perception, illness worry and attachment orientation, 2021, Kallesoe et al

    Abstract now added to original link. Abstract Objective To describe patterns of somatic symptoms, illness perception, illness worries and attachment in adolescents with functional somatic syndromes (FSS) in comparison with a population-based sample of adolescents. Methods Self-reported and...
  9. Andy

    Seeking Care for Long COVID: A Narrative Analysis of Canadian Experiences 2023 Kaufmann et al

    Abstract The goal of this study was to explore the experiences of individuals seeking care for long COVID-19 in the Canadian healthcare system. Recorded virtual interviews were carried out with 8 participants and narrative analysis was used to examine the stories produced and identify the...
  10. Andy

    Long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA... 2023 Yu et al

    preprint: Full title: Long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA from the upper respiratory tract during acute infection. Abstract The incidence of long COVID is substantial, even in people who did not require hospitalization for acute...
  11. Andy

    Preprint: Prediction of Long COVID Based on Severity of Initial COVID-19 Infection: Differences in predictive feature sets... 2023 Socia et al

    Full title: Prediction of Long COVID Based on Severity of Initial COVID-19 Infection: Differences in predictive feature sets between hospitalized versus non-hospitalized index infections Abstract Long COVID is recognized as a significant consequence of SARS-COV2 infection. While the...
  12. Andy

    Beyond the case numbers: Social determinants and contextual factors in patient narratives of recovery from COVID-19 2023 Hitch et al

    Abstract Objective This study aimed to describe and contextualise COVID-19 recovery from the perspective of patient-lived experience, to inform the evolving public health response to the pandemic. Methods Narrative interviews were completed with 37 adult Australians between six and 10 months...
  13. Andy

    Dysbiosis in gastrointestinal pathophysiology: Role of the gut microbiome in Gulf War Illness 2023 Slevin et al

    Abstract Gulf War Illness (GWI) has been reported in 25%–35% of veterans returned from the Gulf war. Symptoms of GWI are varied and include both neurological and gastrointestinal symptoms as well as chronic fatigue. Development of GWI has been associated with chemical exposure particularly with...
  14. Andy

    Thesis Thesis: Investigating the Genetic and Immunological Aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022 Dibble

    Joshua was first author of this publication, Genetic Risk Factors of ME/CFS: A Critical Review. Joshua J Dibble, Simon J McGrath, Chris P Ponting. 2020
  15. Andy

    Genetic Risk Factors of ME/CFS: A Critical Review. Joshua J Dibble, Simon J McGrath, Chris P Ponting. 2020

    Joshua Dibble's thesis is here, Thesis: Investigating the Genetic and Immunological Aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022 Dibble
  16. Andy

    Thesis Thesis: Investigating the Genetic and Immunological Aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022 Dibble

    This thesis describes two investigations into the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), specifically its genetic aetiology and immune system alterations. The first study investigated the genetic basis of ME/CFS using Genome-wide Association Studies (GWAS) by...
  17. Andy

    Long Covid in the media and social media 2023

    BBC News: Thousands of NHS staff with long Covid risk losing their pay https://www.bbc.co.uk/news/health-64405899
  18. Andy

    International: Science for ME social media posts

    News in Brief posts for w/c 23rd Jan. Facebook: https://www.facebook.com/sci4me/posts/pfbid02f4zVMdUm6M466wxeD1X8sN6EfbhPnYHFZpZGLped46htbhmrqYFiQvwTxi5PnUDRl Mastodon: https://med-mastodon.com/@s4me/109774705355923990 and published papers thread Facebook...
  19. Andy

    Pulse: Long Covid training course - Dr Shah

    Assuming of course that he is aware of it.
  20. Andy

    Towards evidence-based and inclusive models of peer support for long covid: A hermeneutic systematic review 2023 Mullard, Greenhalgh et al

    Highlights • Co-produced peer support can help people living with Long COVID. • Increasing the use of effective peer support may reduce health inequalities. • Inclusive peer support can benefit ‘hardly reached’ Long Covid cohorts. • Linking biomedical, relational and socio-political styles are...
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