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It's really starting to feel like M.E is an afterthought disease.

Tread on our RCT published in Lancet’s where we show early treatment with 2-drug combos of fluvoxamine, bromhexine, cyproheptadine, niclosamide in COVID ✔ completely prevented deterioration viral load inflammatory cytokines Long Covid risk

Full Title: Early treatment with fluvoxamine, bromhexine, cyproheptadine and niclosamide to prevent clinical deterioration in patients with symptomatic Covid-19: a randomized clinical trial, 2024, Dhammike Leshan Wannigama et al Summary Background Repurposed drugs with host-directed antiviral...

Persistent immune imprinting occurs after vaccination with the COVID-19 XBB1.5 mRNA booster in humans M. Alejandra Tortoricic; Amin Addetia; Albert J Seo; Jack Brown; Kaiti Sprouse; Jenni Logue; Erica Clark; Nicholas Franko; Helen Chu; David Veesler Highlights XBB.1.5 COVID-19 mRNA vaccine...

https://trials.recovercovid.org/autonomic NIH opens long Covid trials to evaluate treatments for autonomic nervous system dysfunction Part of NIH’s RECOVER Initiative, trials will test at least three treatments for symptoms such as fast heart rate, dizziness and fatigue...

https://www.genengnews.com/topics/infectious-diseases/epstein-barr-virus-has-vulnerable-sites-exposed/

Highlights• Isolated mAbs to EBV gp42, which is required for the fusion of the virus to B cells gp42 mAbs A10 and 4C12 use different mechanisms to inhibit EBV fusion to B cells Two distinct sites were identified on gp42 for receptor binding and for fusion to B cells gp42 mAb A10 prevented...

Merged thread Do people with ME/CFS and joint hypermobility represent a disease subgroup? An analysis using registry data, 2024, Kathleen Mudie et al Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic, multifaceted disease that affects millions globally...

Abstract Background: Although calcium and vitamin D (CaD) supplementation may affect chronic disease in older women, evidence of long-term effects on health outcomes is limited. Objective: To evaluate long-term health outcomes among postmenopausal women in the Women’s Health Initiative CaD...

Background: Coronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19 severity, outcomes, and biomarker...

My daily dose of iron supplementation was 27mg w vitamin C. It took 9 months to bring my ferritin up to 55 from 5 and it would drop back down to 14 within 2 months after I stopped taking iron. Alternate-day administration of 100 and 200 mg taken from the link posted above would make sense...

OXE-103 overview Oxeia Biopharmaceuticals (Oxeia) is a clinical stage biotechnology company that develops drug treatments for mild traumatic brain injury or concussion and underlying neuro-metabolic dysfunction. The company’s lead pipeline candidate includes OXE-103, potent mitochondrial...

The intensity of delayed PEM is only affected by how much I go over my energy limit. Whether I'm 'mild' or 'moderated' doesn't make any difference. My cognitive impairment only started after exercising again in the earlier years.

Oxeia is developing a first-in-class synthetic human ghrelin—an endogenous hormone that crosses the blood-brain barrier—therapy to target the hippocampus. By restoring normal energy metabolism and reducing the toxicity caused by reactive oxygen species (which form in low-energy states), it...

I just want to make a comment about iron supplements in general. I was told to take Palafer many years ago and it was too much (300 mg) to take at once since our body only absorbs 10% and the rest has to be filtered out through the liver which makes us feel sick. This was the best iron...

Conclusion In the past few years, we have made great progress in understanding the mechanism of energy metabolism in migraine. KCL-induced CSD and nitroglycerin-induced cerebral vasodilation are commonly used migraine models, which can cause disorders of energy metabolism and lead to oxidative...

Study will test Humira as potentially preventive treatment in Parkinson’s The trial will assess whether an existing treatment for autoimmune disorders can impede the emergence of Parkinson's symptoms. Hafler and his team have discovered the presence of inflammation in the spinal fluid — the...

https://www.cnn.com/2024/03/07/health/lsd-anxiety-fda-breakthrough-therapy-wellness/index.html No use of psychotherapy Most research with MDMA and psilocybin has relied on the use of trained therapists who meet and establish a rapport with participants before the drug is administered. Those...

https://www.cnn.com/2020/02/27/health/lsd-overdoses-case-studies-wellness/index.html The 49-year-old woman, known as CB, had contracted Lyme disease in her early 20s, which damaged her feet and ankles and left her in “significant pain.” In September 2015, she took 55 milligrams of what she...

New results on efficacy at 12 weeks A single dose of MM120 (lysergide d-tartrate) led to a 48 per cent rate of remission from generalized anxiety disorder at 12 weeks following the drug’s administration, according to MindMed. The MM120 drug also significantly improved clinical signs of...