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#MECFS2023 Next Vishnu Shankar, immunologist in Mark Davis’ lab at Stanford is talking about oxidative stress and suppression of mitochondrial ATP levels in MECFS and Long Covid patients, and reactive oxygen species. He was inspired to work on ME by reading The Puzzle Solver book. September 8...

Canadian Cardiovascular Society Position Statement on POTS syndrome and Related Disorders of Chronic Orthostatic Intolerance This novel classification is on the basis of expert opinion of the Writing Committee on the basis of limitations with the current nomenclature. Suggested diagnostic terms...

Abstract Objectives We aimed to describe the trajectories of cognitive and physical symptoms before, during, and after a positive- or negative SARS-CoV-2 test and in untested controls. Design A prospective cohort study. Setting Norway, 27 March 2020 to 6 July 2022 Participants A total of 146...

Abstract Importance Approximately 55 million people in the US and approximately 1.1 billion people worldwide are postmenopausal women. To inform clinical practice about the health effects of menopausal hormone therapy, calcium plus vitamin D supplementation, and a low-fat dietary pattern, the...

Neuroinflammation was identified across a wide range of brain regions and connected to measures of blood vessel dysfunction https://polybio.org/longcovid-brain-inflammation-associated-with-vascular-problems-harvard-team-finds/

For free speech to be most valuable, it must reach open minds. Open-mindedness suggests an ability to see a perspective outside of one's own. “It's being willing at the very least to have your own viewpoint challenged. Also, to test your thinking a bit,” said Political Science Prof.

Abstract Background Reported orthostatic hypotension (OH) prevalence in Parkinson's disease (PD) varies widely, with few studies evaluating specifically neurogenic-OH (nOH). The ratio of orthostatic heart rate (HR) to systolic blood pressure (SBP) change (Δ) is a valid screening method to...

It would be interesting to hear the discussions on how Prusty will show how ME/CFS differs from long COVID and Wust's presentation on PEM.

How thrilling to see this online after 8 years in the works!!! We showed that #Lyme bacteria mimic our own“don’t eat me” signal with their P66 protein to hide in plain sight!!! This tricks our SIRPa protein to trigger the breaks on immune clearance!

SUMMARY Microglia are implicated in all stages of multiple sclerosis (MS). Microglia alterations are detected by positron emission tomography in people living with MS prior to the formation of structural lesions determined through magnetic resonance imaging. In histological specimens, clusters...

Abstract Innate immunity, the first line of defense against pathogens, relies on efficient elimination of invading agents by phagocytes. In the co-evolution of host and pathogen, pathogens developed mechanisms to dampen and evade phagocytic clearance. Here, we report that bacterial pathogens...

Posting this here for those who aren't on X. Not sure if this is the right place to post this but I thought I would keep it in one place. I am extremely honored to be part of this patient-led initiative for a worldwide congress on Long COVID, #UniteToFight2024/ @U2Fight_World Registration is...

The study was motivated by concerns about the potential harms of restricting or stopping exercise altogether. “We are not saying that the exercise can treat post-COVID,” Tryfonos said. “But we know that not only in post-COVID, in any other disease, if you stop doing exercise in the long run...

Novavax Prepared to Deliver Protein-based Non-mRNA JN.1 COVID-19 Vaccine in Line with WHO Recommendation this Fall LINK

Thank you #UniteToFight2024 for including me in your speaker list. I am hoping to show you how ME/CFS differs from long COVID and how we can predict the severity of long COVID very early. Hopefully it will help us in developing better treatment strategies.

Bonnie Discepolo participated in an clinical trial examining possibly delaying menopause to improve health outcomes. She hopes it gives women more agency. Williams is leading a study to understand the impact of slowing ovarian age on women’s health. The double-blind study looks at 100 women...

April 23, 2024 Will continuous lactate monitoring revolutionize the way we train, or is just another costly sports-science fad? "The important thing to remember is that the lactate is not the cause of your fatigue. It is simply a metabolic marker telling you that you’re working hard...

Abstract Post-exercise reduction in blood pressure, termed post-exercise hypotension (PEH), is relevant for both acute and chronic health reasons and potentially for peripheral cardiovascular adaptations. We investigated the interactive effects of exercise intensity and recovery postures...

Cognitive Impacts of Vestibular Disorders https://vestibular.org/article/coping-support/psychology/cognitive-impacts-of-vestibular-disorders/

I don't think they use this term in Canada. I've never heard of it until I joined the forum.