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  1. OrganicChilli

    Teclistamab-Induced Remission in Refractory Systemic Lupus Erythematosus

    I mostly posted this for documentation because we had a thread on teclistamab the other day.
  2. OrganicChilli

    Teclistamab-Induced Remission in Refractory Systemic Lupus Erythematosus

    Yes, but I don't have an account and therefore no access. But the reddit comment with the link to the PDF is legit.
  3. OrganicChilli

    Prophylactic tocilizumab to prevent cytokine release syndrome (CRS) with teclistamab: A single-center experience

    Teclistamab (Tecvayli®) is a first-in-class T-cell redirecting bispecific antibody that targets CD3 on the surface of T-cells and B-cell maturation antigen (BCMA) on plasma cells [1]. Teclistamab was approved by the FDA for patients with relapsed/refractory multiple myeloma (RRMM) after 4 lines...
  4. OrganicChilli

    Teclistamab-Induced Remission in Refractory Systemic Lupus Erythematosus

    Abstract A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission. Link Full article if you follow the link in the comments (not...
  5. OrganicChilli

    News from Germany

    I thought we were fairly certain endothelial dysfunction and so called "neuroinflammation" aren't a thing in ME/CFS?
  6. OrganicChilli

    News from Germany

    Funded projects The two projects run from May 2025 to April 2026 and are funded with €25,000 each. AI Summary Dynamic Vessel Analysis (DVA) — Retinal Vascular Imaging - Patients with ME/CFS and post-COVID syndrome frequently show signs of endothelial dysfunction and reduced blood flow in...
  7. OrganicChilli

    Sleep problems in ME/CFS - discussion thread

    Same here. I don't have any other sleep disturbances and my sleep is refreshing unless I've overexerted which then leads to PEM the next day.
  8. OrganicChilli

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    And not just OMF. He's also funded by WE&ME. That's a shame because I think they're able to collect a decent amount of donations. https://nitter.net/BhupeshPrusty/status/1954967266367508547#m They have Ron Davis and Putrino on their scientific advisory board.
  9. OrganicChilli

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    Does this really impact his funding? Does anyone who reads a grant application care about his influencer status? Is this why Prusty announces his papers on Twitter?
  10. OrganicChilli

    Pediatric Long COVID Is Characterized by Myeloid CCR6 Suppression and Immune Dysregulation

    Abstract The biological mechanisms underlying long COVID in the pediatric population are poorly understood. Our study aimed to characterize the immune pathophysiology of long COVID in children and young people (CYP). We analyzed major immune cell compartments in PBMCs, as well as specific...
  11. OrganicChilli

    News from Germany

    Unfortunately in Germany it's almost always mandatory to attend rehab centres in order to qualify for ill health retirement. It's funded by pension providers and health insurers. Absolutely insane system.
  12. OrganicChilli

    News from Germany

    https://www.spektrum.de/news/wie-bayern-seine-kurbaeder-mit-long-covid-patienten-therapiert/2283420 How Bavaria is treating its spa resorts with Long-Covid patients
  13. OrganicChilli

    The symptom signaling theory of ME/CFS involving neurons and their synapses

    But do we know much about post-concussion syndrome? My impression is it gets treated like ME/CFS by doctors along the lines of "There's no visible damage in your brain and you just need more exposure to light/noise/any other triggers and it's all just anxiety."
  14. OrganicChilli

    DecodeME in the media

    The Guardian podcast: https://www.theguardian.com/science/audio/2025/aug/21/can-science-crack-the-mystery-of-me-podcast
  15. OrganicChilli

    News from Germany

    Scheibenbogen is a great advocate, but she seems to be one of the many researchers married to a specific hypothesis. I don't think 10 years is an outrageous estimate and I suspect a few of Scheibenbogen's statements are exaggerations to get her point across.
  16. OrganicChilli

    Do you have fever as a part of PEM?

    Who's that?
  17. OrganicChilli

    Do you have fever as a part of PEM?

    I have measured it! And the result was no fever, but I definitely felt feverish.
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