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  1. Mij

    Feeling worse from oversleeping—poll

    I only get that groggy over slept feeling when I first wake up, but once I get up and start moving around for 10 minutes I'm feeling ok. This is a more fragmented type sleep and I have very bizarre dreams. I also experience that dead weight can't move deep sleep aching feeling during the day...
  2. Mij

    Covid-19 vaccination experiences

    Children from struggling families to be offered jabs at home "The pilot scheme was part of that aim, he said, targeting families who are not signed up to a GP surgery or face language barriers, travel costs or childcare issues which stop them getting to a doctor. Uptake of childhood vaccines...
  3. Mij

    B12/Folic Acid and D3/K2 Supplementation

    Date: December 30, 2025 Source: Vanderbilt University Medical Center Why your vitamin D supplements might not be working Summary: A randomized trial from Vanderbilt-Ingram Cancer Center reveals that magnesium may be the missing key to keeping vitamin D levels in balance. The study found...
  4. Mij

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    Really. I thought it was a bit odd that he signed his name after his posts.
  5. Mij

    Combined magnetic resonance imaging and serum analysis reveals distinct multiple sclerosis types, 2026, Charles Willard et al

    Abstract Multiple sclerosis (MS) is a highly heterogeneous disease in its clinical manifestation and progression. Predicting individual disease courses is key for aligning treatments with underlying pathobiology. We developed an unsupervised machine learning model integrating MRI-derived...
  6. Mij

    Why is showering so PEM/OI inducing

    One thing I can not do is take a very short shower after power walking. I have to go to bed feeling sweaty which is the price I pay. I can scrub my feet which feels good. So even if I feel good after my walk, the shower thing is too much and I get a chest pressure feeling and my arms feel...
  7. Mij

    Why is showering so PEM/OI inducing

    Same with eyes closed. I prefer showering in the evenings, mornings are not so good. I am able to stand during a shower for many years now, but I still have to sit when my arms are up washing my hair and stay sitting while rinsing. I feel weak quickly if I try to wash my hair while...
  8. Mij

    Antigen-specific CD8 T cells are generated and reactivated in the bone marrow following viral brain infections and impact the bone marrow niche, 2025

    Abstract Bone marrow is the primary immune organ responsible for stem cell maintenance and hematopoiesis. However, the contribution of the bone marrow niche for the generation of adaptive immune responses is less well-understood. We therefore assessed the capacity of virus antigen-specific CD8...
  9. Mij

    Chronic Reactivation of Persistent Human Herpesviruses EBV, HHV-6 and VZV and Heightened Anti-dUTPase IgG Antibodies... 2025 Ariza et al

    Also mentioned in this study: Reactivation of Latent Herpesviruses and a Faulty Antiviral Response may Contribute to Chronic Multi-Symptom and Multi-System Illnesses in U.S Military Veterans
  10. Mij

    Preprint Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest, 2025, Charlton, Wust et al

    "We have some more new data on this shift. Happy to show in Hamilton in April;)"
  11. Mij

    Covid-19 vaccination experiences

    I've had 8 vaccines so far, both Pfizer and Moderna with the same results for both. Sore arm for 2 days. The latest vaccine last month was Moderna and I didn't have a sore arm at all. I had both flu and Covid at the same time. Some friends only want Pfizer and order it ahead of time.
  12. Mij

    Metabolomics-Based Machine Learning Diagnostics of Post-Acute Sequelae of SARS-CoV-2 Infection, 2025, Ethan Cai et al

    Abstract Background: COVID-19 has taken millions of lives and continues to affect people worldwide. Post-Acute Sequelae of SARS-CoV-2 Infection (also known as Post-Acute Sequelae of COVID-19 (PASC) or more commonly, Long COVID) occurs in the aftermath of COVID-19 and is poorly understood...
  13. Mij

    Effectiveness of the 2024–2025 KP.2 COVID-19 vaccines in the United States during long-term follow-up, 2025, Ioannou et al.

    Wastewater signals in my city for Covid is very low, but the flu signals are super high.
  14. Mij

    Is PEM cumulative? - public thread

    PEM is cumulative, don't be fooled into believing that 'the next time' will be better because it won't.
  15. Mij

    Menopause hormone therapy and risk of mild cognitive impairment or dementia: a systematic review and meta-analysis, 2025, Melville, MSci et al

    Summary Background Globally, dementia disproportionately affects women. Changes in circulating sex steroids over the menopause transition might contribute to this sex difference. Menopause hormone therapy (MHT) is recommended by the UK National Institute for Health and Care Excellence to manage...
  16. Mij

    Parkinson’s breakthrough changes what we know about dopamine

    Dopamine isn't the brain's throttle- it's the oil that keeps movement running, and the insight could change Parkinson's care Date: December 22, 2025 Source: McGill University Summary: A new study shows dopamine isn’t the brain’s movement “gas pedal” after all. Instead of setting speed or...
  17. Mij

    Temporal dynamics of the plasma proteomic landscape reveals maladaptation in ME/CFS following exertion, 2025, Germain et al.

    I'm having difficulty understanding what they mean by "repair" in the linked article that was posted.
  18. Mij

    Temporal dynamics of the plasma proteomic landscape reveals maladaptation in ME/CFS following exertion, 2025, Germain et al.

    "Exercise is Not Producing Muscle Damage in ME/CFS: PEM May be All About Muscle Repair" Delayed PEM affects all muscles whether I'm using them or not during exercise. If I go over my energy boundary and experience delayed PEM from walking, my whole body feels a loss of power/ weak, including...
  19. Mij

    News from PolyBio Research Foundation

    "Looking back at some of PolyBio’s most influential moments of 2025–we can’t forget about this collaborative effort between Dr. Iwasaki’s Yale team & Dr. Bragée’s ME/CFS clinic in Sweden. The PolyBio-supported study used cerebrospinal fluid to identify 2 distinct ME/CFS subtypes".
  20. Mij

    Repurposed Drug May Delay Menopause, Slow Ovarian Aging

    Columbia Fertility’s VIBRANT study examines the impact of rapamycin on ovarian aging. Effect of Rapamycin in Ovarian Aging (Rapamycin)
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