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  1. bicentennial

    Hypotheses and Research Directions for ME/CFS

    (2015) Structural and functional implications of the interaction between macrolide antibiotics and bile acids -PubMed (2016) Bile Acids in Neurodegenerative Disorders - PubMed (2020) Bile Acid Signaling in Neurodegenerative and Neurological Disorders - PubMed (2020) Bile Acid Signaling in...
  2. bicentennial

    Hypotheses and Research Directions for ME/CFS

    Maybe a varied PEM delay correlates to a varied stool transit time with an encyclopaedic, sequenced array of connections A gut upset is not required in a working theory that some part of the encyclopaedic, sequential, digestive and metabolic process - is involved in the delay of PEM. But also...
  3. bicentennial

    Enduring symptoms: A call to immediate action, 2025, Barnes

    the rcp journal edited out the biophysical approaches to ME/CFS, and it edited out the biophysical patient perspective on ME/CFS. This after the rcp executive was overturned by its own members who objected to it making physicians liable for physician associates And if they do not rehaul their...
  4. bicentennial

    News from the USA, United States of America

    That article - on highly organised infection - reports the chronic aftemath as specifically "confirmed" by thousands of research reports: "Thousands of research papers on PubMed and other healthcare databases now confirm that repeat reinfection from SARS-CoV2, the virus causing covid, is...
  5. bicentennial

    News from the USA, United States of America

    Well now that's out in the open, the project of the year I would like to know if this Is proven by conclusive research or still only indicated by preliminary research I am sure that was the initial UK policy as reported in the news at the time, then silenced. but ... recurrent Happily no-one...
  6. bicentennial

    UK: Disability benefits (UC, ESA and PIP) - news and updates 2024 and 2025

    As stated in this case the disability and its requirements are consistent with the applicable law and its provisions for the management of chronic illness and disability, hence the newly revised guidelines, guidance and planned delivery still being implemented by dwp and so overlooked to date -...
  7. bicentennial

    Germany's "National Decade Against Post-Infectious Diseases"

    So who will apply or be proposed as the international reviewers, required to be independent of the German experts, institutions and "consortia" which may need structure to modify their assumptions. So may international counter-parts. Several bio-medical professionals, scientists and...
  8. bicentennial

    Let's talk wheelchairs and mobility scooters

    thankyou @Kitty, that clarifies a lot for me. It certainly is a complex technology and high quality tech matters a lot. Maintenance must be manageable, especially if there are long periods when unable to to access or organise it. So - about trickle charging: Thats very useful if weekly access...
  9. bicentennial

    Let's talk wheelchairs and mobility scooters

    I think some mobility scooters require a trickle-charge type of battery. When not in use these batteries must be left charging on a mains, that keeps its charge topped up. Then too long without the trickle-charging would wreck the battery. Also it is said that an extension lead for the mains...
  10. bicentennial

    Germany's "National Decade Against Post-Infectious Diseases"

    "promotional, not informational" - this systemic dissonance is sinking governments while soaking up government subsidy - not what it says on the tin So buyer beware So this German program would rely on effective management at the level of authorisation, with a rigorous criteria - for each...
  11. bicentennial

    United Kingdom News (including UK wide, England, NI and Wales - see separate thread for news from Scotland)

    Which is why the medico-legal ultimatum was spelt out to them by the Covid Airborne Transmission Alliance (CATA), and BOHS, as now in this BOSH guidance: COSHH and Healthcare Respiratory Protection - which I found tucked away in the news provided above by Chandelier with the AI summary that...
  12. bicentennial

    News from the USA, United States of America

    What on earth did President Trump have and hold against the nurses?
  13. bicentennial

    bodysymptoms.org: Postlaunch evaluation and update, 2025, Saunders et al

    In the 1990s and the 2020s: Oh no said the service personnel, we don't do that any more, everyone knows better now, and then they did it all over again. New-broom script. Stand clear. The same hymnbook - and for starters (entry level): Professional Certificate in Psychosomatic Medicine Or...
  14. bicentennial

    USA: The RECOVER Initiative - Long Covid research

    I think "Status: withdrawn" may mean its closed for further recruitment. I think we need to know how a diagnosis of Alzheimers and its related dementias is confirmed. I don't trust psychological tests alone to diagnose such things. Too many overlaps and resemblances. A neuro-cognitive...
  15. bicentennial

    USA: The RECOVER Initiative - Long Covid research

    Sorry, I forgot the link: REVERSE-Long COVID-19 With Baricitinib Study (REVERSE-LC)
  16. bicentennial

    USA: The RECOVER Initiative - Long Covid research

    Sadly, there was talk of neuro-psychiatric psychosis associated with Long Covid. "Alzheimers-associated" implies some pathological finding of neuro-degenerative disease. But cognitive impairment does not mean dementia, except where someone was trained to assume that it is equivalent, which I...
  17. bicentennial

    USA: The RECOVER Initiative - Long Covid research

    Thankyou. 1st time I saw this profile acknowledged in print. I dare not say "cognitive impairment" (ME / CFS-associated), since I was told in that case I cannot make an appointment, conduct a transaction, arrange a service, hold a conversation, must be stopped there, find a 3rd party.... ...of...
  18. bicentennial

    United Kingdom: ME Research UK (MERUK) News

    Thankyou. I wonder - if no-one overstated the evidence, not even a little - would everyone have got more focused on narrowing down the scatter and progressing the research, a lot further, and conclusively. A little overstatement can skew a lot. Its not great if research proposals are not all...
  19. bicentennial

    United Kingdom: ME Research UK (MERUK) News

    I don't know how this is known, I know my brain and muscle don't work properly, so I was very inclined to agree .. except its a big claim to be reporting as if endorsed. The specifics given got me thinking - maybe my brain cells and muscle cells work fine, if something else went wrong. I like...
  20. bicentennial

    Australia: News from Griffith University, National Centre for Neuroimmunology and Emerging Diseases (NCNED)

    I thought Dr Shepherd was the MEA Medical Advisor assessing the mysteries of science for the Members. The MEA also has in-house and external professionals assessing research news and research proposals. Maybe they were all off-sick. It is not clear from this snippet why the MEA does not...
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