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  1. spinoza577

    CFS and FND in context of "Functional cognitive disorder" in "Non-Dementia Pathways Guidance" from London Dementia Clinical Networks, Jan 2020

    Very well noticed. It may work like so: As long as there is a problem as along there will be an explanation. For practical reasons they turn their attention to the minding as the body is utterly complex - ironically this may happen subconsciously. Indeed and but, that there is for sure a medical...
  2. spinoza577

    Comprehensive Circulatory Metabolomics in ME/CFS Reveals Disrupted Metabolism of Acyl Lipids and Steroids: Levine,Hanson et al 2020

    I wonder this too, aside from individuel differences there might be differences due to areas, seasons, and daytime. It could also point simply to an exaggeration. My personal impression is that it is pretty unlikely that the findings in metabolism and the immune system give a direct cause. They...
  3. spinoza577

    Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test, 2019, Morten, Newton et al

    I don´t see in any way how a mt problem could explain delayed PEM and the up and downs in the long course of illness. That single symptoms come and go would not be explained either.
  4. spinoza577

    CFS and FND in context of "Functional cognitive disorder" in "Non-Dementia Pathways Guidance" from London Dementia Clinical Networks, Jan 2020

    I think rote may actually the core of learning any medicine, and then the doctors simply are applying it. I even can understand that doctors don´t want to step away from what they have learned and what they can do without getting criticized from the whole machinery. Sadly so far there is not...
  5. spinoza577

    Dealing with the unknown. Functional neurological disorder (FND) and the conversion of cultural meaning, 2020, Canna and Seligman

    And I considered myself already as having quite some fantasy! Probably I should apologize for not having digged much into psychiatric theories. Thank you for clarifying. - On the other side, the title is, "Conversion OF cultural meaning", so first read is, the cultural meaning converts into...
  6. spinoza577

    Patients with ME/CFS and chronic pain report similar level of sickness behavior as individuals injected with bacterial endotoxin... 2019, Jonsjö et al

    It is simply a guess. Therefore I don´t see why here a fallacy should occur. The guess they believe in they then tried to elaborate. I don´t see any problems with that. I also don´t see a priori any inconvenience with the try to explain ME/CFS via nerves. (In fact I personally find this to...
  7. spinoza577

    Dealing with the unknown. Functional neurological disorder (FND) and the conversion of cultural meaning, 2020, Canna and Seligman

    What are they talking about? About a cultural determination of such seizures? Or about a cultural co-deterimanation of such seizures? Noteworth is, that the determination of incapabilitiy of these seizures with neurological disease is of course a medical one, so another one - it´s already bad...
  8. spinoza577

    Dealing with the unknown. Functional neurological disorder (FND) and the conversion of cultural meaning, 2020, Canna and Seligman

    It gets better and better. They finally will say that their lack of thinking accurately is just succeeding to heal the patients from their inaccurate illness.
  9. spinoza577

    Action CIND Webinar: "Why Working out Doesn’t Work" by Workwell Foundation

    I think they don´t manage to grasp the nature of PEM. It is rather a pattern of occurence (of symptoms), not a pattern of concrete symptoms. The CCC may serve a confusion, as they give an alternative to PEM called PEF. "Malaise" obviously referres to symptoms felt in the body, whereas...
  10. spinoza577

    ME/CFS patients exhibit altered T cell metabolism and cytokine associations (2019) Mandarano, Hanson et al

    I am a fan of low manganese food, and had just a look: Decreases in CD8+T, naive (CD4+CD45RA+) T, and B (CD19+) lymphocytes by exposure to manganese fume Nakata et al 2006, open access. I think it could be related, only that exposure is without infection but with high amounts.
  11. spinoza577

    Well known, famous people reported to have Lyme Disease.

    I want to basically agree with that. I have been tested positive for Lyme ("compatible with late stage Lyme") with ELIA and western blot. But the impact may be lasting even without persistent borrelia, at least in case of the nervous system. My test even might be wrong, as earlier tests (though...
  12. spinoza577

    Denmark: Open letter to health politicians from Danish ME Association with impressive list of signatures

    I don´t exactly get what you are asking, but I would think that the authors wanted to provide the readers with two impressive examples of pointful research or considerations underlying their apply. I don´t know about the paper attributed to Hornig, but I think that both (with their statements)...
  13. spinoza577

    Psychiatry Advisor: Addressing depression in ME/CFS, 2018, Cindy Lampner

    This may be the point: with depression you are not interested in things in any means, you don´t see any sense in doing things, but with only anhedonia you rather would like to do things, you´re interested in things in their whole presentation, but in the details - which are necessary part of...
  14. spinoza577

    The role of low-grade inflammation in ME/CFS (Chronic Fatigue Syndrome) - associations with symptoms, 2019, Jonsjö et al

    The CCC in fact has AN alternative: post-exertional-malaise or post-exertional-fatique. Out of the context it seems that the authours/contributers are referring to the distinction "physical"/"mental" symptoms - which is clearly thought to differ in me/cfs even though the SINGLE symptoms are...
  15. spinoza577

    The role of low-grade inflammation in ME/CFS (Chronic Fatigue Syndrome) - associations with symptoms, 2019, Jonsjö et al

    Thank you for the quotes, emotionally difficult to read through, even though their words are not worth much: "in the absence of ... verfiable disease" ???? it´s rather crime to assume that there never can be found a physiological disease in ME/CFS It is also improper not to evaluate the...
  16. spinoza577

    The role of low-grade inflammation in ME/CFS (Chronic Fatigue Syndrome) - associations with symptoms, 2019, Jonsjö et al

    A small glimpse on the paper from page 6: - They say to have found an association between CCL11 and cognitive impairment in ME. https://en.wikipedia.org/wiki/CCL11 - Furthermore they say, beta-NGF would be associated with PEF, significantly negative in women, and non-significantly positive...
  17. spinoza577

    The role of low-grade inflammation in ME/CFS (Chronic Fatigue Syndrome) - associations with symptoms, 2019, Jonsjö et al

    I would say, in the essential meaning of the word, yes: you feel worse soon after exertion, when you are ill. But in ME/CFS the term may include distinct properties: it can appear delayed, and with a regularity - it would be a strange infection or damage which would occur, say, 24 h later, in...
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