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https://onlinelibrary.wiley.com/doi/10.1111/jth.14981 Parallels with systemic inflammatory disorders such as atypical hemolytic uremic syndrome (aHUS) have implicated the complement pathway in the pathogenesis of COVID-19, and particularly the anaphylatoxins C3a and C5a released from cleavage...

Anti psychiatry or as I call it no evidence no illness brigade hijacked M.E They are pro psychological explanations. An example of Anti psychiatry thinking https://livingwithschizophreniauk.org/information-sheets/the-anti-psychiatry-movement/

Does anyone identify more with long covid without the lung part,well before long covid.

Is there a possibility the liver is the key,I suspect I have partial aHUS and see common features Is the liver damaged altered or triggered causing a complement imbalance and over reaction to viruses Mild aHUS,low iron,low platelets and kidney haematuria and thickened blood due to complement...

https://ahusnews.com/2022/01/12/same-c5a-complement-protein-mechanisms-ahus-covid-19/?fbclid=IwAR1DsInEnl6-7BVEmT5-yy2WT3gw_x4NqNEGTuW5rp2OrceLF8SJVQohew0&cn-reloaded=1 Same C5a Complement Protein Mechanisms Found in aHUS, COVID-19

Does plasma viscosity show this

Is this similar to the covid finding of snake venom mimick Low complement c3 will mimic this I think

Low complement c3 mimicks snake venom effect I suspect I have inherited mine In addition to studying C3 deficiency in diagnosed human patients, researchers have studied C3 deficiency in animals. C3 deficiency can be induced by injecting animals with cobra venom factor, which functions like an...

Study centre for complement https://complement.org.uk/ complement deficiency https://en.m.wikipedia.org/wiki/Complement_deficiency

Would rituximab be worth trialling for long covid

I’m low on platelets,maybe being activated is using them up

https://www.thebrspecialist.com/?fbclid=IwAR0d1x06V7kPidWDrRNrYMuBmJ0Iy7KGcr_hQbCaJciij22XRSu7-NDN0qE https://www.plymouth.ac.uk/staff/michael-hyland

What region is that on chromosome 4 I wonder

I purchased sodium dichloroacetate for a suspected pyruvate dehydrogenase deficiency but still have it on hold as I have concern over potential side effects

https://www.leeds-live.co.uk/news/leeds-news/leeds-doctor-cant-work-drive-22935904.amp https://news.sky.com/story/doctor-with-long-covid-who-suffered-violent-shakes-and-hallucinations-attacks-boris-johnsons-plan-to-end-all-coronavirus-rules-12543375

l-Arginine increases NO I just trialled a small amount and not sure if it was something I’d try again I tried it as it’s mentioned in relation to CADASIL and wonder if a partial cadasil may exist and could it be more common

Would a skin biopsy show anything

https://pubmed.ncbi.nlm.nih.gov/32274570/ COVID-19 in the heart and the lungs: could we "Notch" the inflammatory storm?

https://www.frontiersin.org/articles/10.3389/fcvm.2021.681948/full The Notch Pathway: A Link Between COVID-19 Pathophysiology and Its Cardiovascular Complications Abstract COVID-19 is associated with a large number of cardiovascular sequelae, including dysrhythmias, myocardial injury...