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  1. J

    Breathwork

    Anyone have experience with any of the popular breathing exercises, such as the Wim Hof Method, Yogic Pranayama, or Holotropic breathwork? I've dabbled into it just a little and found it relaxing, but I worry the intense breathing could give me post-exertional malaise of my diaphragm, and I also...
  2. J

    Trial of CT38 for ME/CFS by Cortene Inc.: big claims being made...

    There have been several inferences made that the Cortene group is signing off on Cort's blogs. If Cort has been mischaracterizing their hypothesis i'm sure they would have something to say about it. Care to point out where on the Cortene website, or anywhere else for that matter, that it says...
  3. J

    Trial of CT38 for ME/CFS by Cortene Inc.: big claims being made...

    Cortene's model accounts for how ME patients typically have low cortisol, not high.
  4. J

    Trial of CT38 for ME/CFS by Cortene Inc.: big claims being made...

    One of the steps in the Cortene group's hypothesis is a desensitization of the 5HT1A receptors. Wouldn't this suggest that a 5HT1A agonist could be another possible drug target? I know the drug Buspirone is a 5HT1A agonist but I have heard that pwME dont tolerate it very well. Thoughts?
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