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Possibly, but contrary to the 36% figure from the Hjóbratsson paper, the MetaBLIND study is often cited nowadays to justify that blinding is not essential for PROMs despite its methodological shortcomings. @ME/CFS Skeptic has had a helpful article published about this in the Journal of Health...

Thank you @Hutan. I have read some of the literature on functional dyspepsia and, interestingly, it mentions duodenitis (inflammation of the duodenum) which showed up on a gastroscopy that I had two months after getting a bad bout of gastroenteritis on a trip abroad in 2018. Gastritis also...

I am bedridden with severe ME and am struggling to maintain my weight because digestion is very harsh on me. The more I eat throughout the day, the harder digestion becomes, so I cannot eat enough. I have lost a significant amount of weight over the last months, to the point that I have become...

Mentions ME/CFS as a central sensitization disorder that fits within the fear avoidance model; says that avoiding tube feeding is “more likely to promote recovery”:

(Bolding mine) The decision to commence jejunal feeding in patients with structural abnormalities, which prevent oral or intragastric feeding, is usually straightforward. However, decisions surrounding the need for jejunal feeding can be more complex in individuals with no clear structural...

As the title asks. “Well recognized” means that the diagnosis is uncontroversial in conventional medicine. The obvious one is Alzheimer’s but there may be other such syndromes and diseases. If considered to be neurological diseases, or at least primarily biological in nature, this applies to...

One can only wonder what a kid editor reading a FND paper from the likes of Stone, Carson, Perez or Edwards would say.

I started at 0.5 mg but it gave me insomnia, even when I took it at the beginning of the afternoon (when I wake up). Anecdotally, insomnia is supposed to dissipate after a few days of treatment but since I am bedridden with severe ME, I cannot afford any further deterioration from a lack of rest...

While the section for patients on the website is revealing about IMPARTS’ approach (the usual BPS fear avoidance and deconditioning model), it gives shocking ableist advice given 1) the cardiovascular and respiratory complications caused by Covid, 2) the disregard for vulnerable people in...

Dr Clarke is close to Simon Wessely and Clare Gerada, judging by her many and friendly interactions on Twitter with them (she often replies to Wessely’s tweets) from 2016 to today. She has gone so far as to call him a “legend” and has done podcasts for the Royal Society of Medicine with him...

Without wanting to delve into politics — moderators, please remove this post if it breaks rule 12 — it seems strange that a marxist-leninist party fails to see that the Waddell-Aylward biopsychosocial model is quintessentially capitalistic, in that it focuses on reducing healthcare costs and...

The situation in London seems to be the opposite of what is happening in France — few people have gotten boosted this fall (though there was an uptick before the end of year festivities) so there is a surplus of vaccine doses. The nurse who vaccinated me at home was able to get a prefilled...

This is reminiscent of psychiatrists and psychologists who have distance-diagnosed controversial political figures such as Trump, so breaking the Goldwater rule to generate polemics for the sake of entertainment in the media seems commonplace.

When I read Dr Husain’s testimony, I could not figure out the point he was making (if any). As I understand it, an expert testimony is meant to address one or more issues raised throughout the guideline development process, but his was no more than a description of the services he provides as a...

After an appeal by Janssen (the pharmaceutical company that manufactures esketamine) in July, NICE reviewed the evidence they submitted again in a technology appraisal guidance (TAG) and recommended against its use for treatment-resistant depression. The TAG committee’s discussion is an...

It is hard to give them the benefit of doubt given their shenanigans - refusing to release data from a publicly funded trial, molding results to their wishes by downgrading the definition of recovery and dropping out actimetry, publishing objective outcomes separately, and so forth. This has...

My mother has had anosmia since her youth, after a bad bout of an undetermined infection. She shows very little interest for food and she says that she would not mind eating the same foods everyday. That is not the case at home because my father cooks for both of them, but she often does so when...

The 43% effectiveness rate is an absolute one (all groups included). The CDC conducted a subanalysis by time since the last monovalent dose (Table 3) and found that the effectiveness against infection of the bivalent booster compared to people who received their last monovalent dose 8 months ago...

This may be a trivial thought, but I find that the improvement in the “standard medical care” group at follow-up which led it to catch up with the improvement in the GET group is the nail in the coffin for GET. Assuming that it was indeed GET that led to an improvement in the active group...

About conflicts of interest, the PACE trial investigators (and possibly FND leaders) have done paid consultancy work for health insurance companies. In this 2019 Nature news article about CoIs in psychological research, Alan Carson is quoted twice as associate editor of the JNNP, advocating for...