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  1. L

    The role of the Thymus gland in ME?

    You could be right and maybe the overactivation could not be enough to stop the disease process. The immune modulator I use mimics a thymus hormone.
  2. L

    Intermittent cloud urine anyone?

    Can't you buy strips to test for protein, glucose etc?
  3. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    It does not push me. It relaxes. It stopped the racing brain. When I started to take it the big suprise was that it eased the pain enough to let me sleep for a few hours. A very long time ago it was claimed it can bring the immunesystem back to normal. Low and high dosis have opposite...
  4. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    The plasma elimination half-life of levamisole is fairly quick at 3–4 hours. The metabolite half-life is 16 hours.
  5. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    Levamisole is metabolized to aminorex. That is why it is forbidden in horseracing.
  6. L

    Shooting Pain in Leg and Finger Tip on Left Side

    Sometimes but it is not so bad anymore and very local.
  7. L

    Shooting Pain in Leg and Finger Tip on Left Side

    In had the shooting pains all over my body. I still get it sometimes but it is much more superficial now and hurts less. Itching sometimes drove me mad. Does the itching come after the shooting?
  8. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    I was dying . Now I am mild to moderate. I have been taking it for almost 25 years now. Lasting improvement was and still is slow. Onset started with what seemed the worst flu ever. Never fully recovered and became slowly worse.
  9. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894934/
  10. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    Role of α7 nicotinic receptor in the immune system and intracellular signaling pathways https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655390/
  11. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    https://www.academia.edu/35915156/The_Interactions_of_Tryptophan_and_its_Catabolites_with_Melatonin_and_the_Alpha_7_Nicotinic_Receptor_in_CNS_and_Psychiatric_Disorders_Role_for_the_Aryl_Hydrocarbon_Receptor_and_Direct_Mitochondria_Regulation
  12. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687317/ http://www.uss.cl/newsletter-uss/wp-content/uploads/sites/19/2016/05/Positive-modulators-of-the-α7-nicotinic-receptor-against-neuroinflammation-and-cognitive-impairment-in-Alzheimers-disease.pdf...
  13. L

    Why does levamisole help me? Mitochrondia, a7nAchR, Tryptophan

    levamisole is an allosteric modulator of a7nAchR https://journals.sagepub.com/doi/pdf/10.1177/1178646917691738 https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.12235 https://pdfs.semanticscholar.org/490f/ec1709c39d335f18226144c80b33a9384bfb.pdf...
  14. L

    What does fold change mean?

    That must be in the paper.
  15. L

    Dogs Are Dying Suddenly in Norway

    More likely something escaped from defrosting northpool grounds.
  16. L

    Maureen Hanson talk at OMF Symposium 2019

    Any stressor can make it worse. Anyone might be infected but the immune system can keep it in check. Then a stressor strikes and it reveals.
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