There are two conclusions one can form after reading Wessely's study the first is there is little difference between depression and CFS. The...
This brings home the point. By "normal" they meant within or above 1 SD of normal, which assuming a gaussian distribution would be the top 84%...
That isn't the only one they initially looked at though. So you have to correct for multiple comparisons and the odds go way down. When 90% (or...
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To claim the wait period before a treatment is a "control" is laughable.
Or quality... Those professionals who think it is unimportant to critically read the method and results of a study, when you can just read the...
There is no magic cutoff, because it is a self report questionnaire with limited scope. In the real world, data like this is not clean. It's not...
It's officially give awards to your mates season again!
The problem is there are hundreds if not thousands of possibilities that fit that criteria.
This is true, but I think the overall point remains - a Randomised Controlled (blinded comparison group) Trial is the minimum level of evidence...
I think Larun's argument is ridiculous because the patients who really don't like GET would never consent to participate in such a trial in the...
Not to my satisfaction, no.
They still haven't bothered to ask patients with specific illnesses (and different backgrounds) whether these questions are understandable/easily...
I've had a lot of trouble trying to pin that down before...
The manuscript is decent but if you can't achieve significance with 49/48 patients, well, I doubt the therapy is very good.
See also: What is “evidence” in psychotherapies? Scott O. Lilienfeld https://onlinelibrary.wiley.com/doi/full/10.1002/wps.20654?af=R
Despite all the rhetoric, rates of antivaxxers are not increasing and vaccination rates are at or near all time highs in almost all countries...
Sure, "pragmatic" trials can only ever be considered 'suggestive' quality evidence (along with case studies and pilot studies). The question is...
Most likely explanation is that it is a coincidence, with natural remission. I'd be very sceptical of anything less than a blinded pilot study.
There was substantial drop out rates, it is hard to say if this biased the results. I don't understand why they didn't include T2 results in...
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