I think the main problem is that this flaw - a focus on subjective outcomes in unblinded trials with inadequate controls - is so widespread. If...
That would be alright. A lot of doctors (pretty much all doctors in Belgium) think CFS is just long-lasting fatigue or something like a burnout....
I think that figure of 5% comes from the review by Cairns & Hotopf on the prognosis in ME/CFS. It almost 15 years old (and the data in it even...
It's a concept that is used in other illnesses as well, especially chronic (low back) pain if I'm not mistaken. See for example: [MEDIA]...
The fact that they reported these negative findings - which speaks against their hypothesis - suggest that their data could have shown a boom and...
They don't give any data on this. It isn't even mentioned in the results. Bit it isn't my Interpretation that there was no boom and bust pattern,...
That's possible. If you focus on 1 patient then you certainly have to follow up on him/her for a longer period of time to see boom-bust patterns....
So they couldn't find a boom-bust activity pattern. I also think they don't use that reference correctly. 17 refers to Van der Werf et al. 2000...
I don't think this is good news. I'm afraid they'll just tweak it a little and that the main flaw (a focus on subjective outcomes in unblinded...
Actually, I think he phrases it rather well. He says there are all these papers that show there is an underlying pathology that we just haven't...
Moderator note: merged thread. Link: https://www.nytimes.com/2019/06/13/health/fecal-transplant-fda.html
Just found another reference for this, a letter from Prins, Bleijenberg en Van Der Meer in the Lancet. It was a response to the 2001 report by...
Well done @Andy ! I was a bit surprised by their answer to the question of whether the handgrip strength test could do a few more repeats to see...
I assume you mean this one: Voermans et al. (2010) Fatigue is a frequent and clinically relevant problem in Ehlers-Danlos Syndrome.
I wrote an email to the editors and they said they expect it to appear next week.
Good point. But if ME/CFS patients would repeatedly show a different gut microbiome composition compared to healthy controls, and if other...
Did a quick scan of the papers and I don't think there is a study that reported reduced blood volume in ME/CFS patients compared to controls....
It would be interesting if we could work out which findings seem most robust or promising in ME/CFS research. I was thinking of: Increased...
I don't really have an analysis. From reading the overview of Van Campen, I got the impression that most studies have found negative results (I...
Something similar can be said of the cytokine and NK-cell studies. Cytokine studies usually contradict each other and there isn't really a pattern...
Separate names with a comma.
