That appears to be non sequitur to my quoted comment, Peter, which was that most of these studies turn out to be artefact. They are not for...
It looks as if by psychosomatic they simply mean mind and body - as in sound in mind and body. In which case we all want to have a good...
I have uploaded a review of nutritional problems in severe ME/CFS to the open access journal Qeios. It should be available by Monday. Qeios...
The basic point is that EDS is defined as a monogenic dominant or sex linked recessive disorder. There has always been a group called type III, or...
As far as I can see this is just a report of a gene variant in two families with EDS. I would forget the hEDS. In these families it is presumably...
I thought it was that the foods stimulated release of histamine. Do any foods actually contain a lot of histamine? Histamine wouldn't produce an...
I am not clear that either of these are meaningful? A number of foods stimulate histamine release in the GI tract - strawberries and seafood I...
I am afraid it is just a word salad, @Hutan. Anyone familiar with the clinical pathology of inflammation can see that they do not actually think...
It's actually completely meaningless, I think, @Hutan. As are the data on interferons I think. One of the authors here is a serious red flag in...
It is reasonable to question why there should be scepticism, but from my perspective the scepticism is founded on years of experience with this...
Almost nothing is known about turnover of these wall signals. But observations on rheumatoid nodules suggest that the signals are dependent on...
It would require some careful systematic work to establish normal patterns. Maybe Rob Wust's group might have an interest in looking at muscle.
The increasing emphasis on amino acid metabolism in ME/CFS seems interesting. A shift in metabolism that might in a crude sense be...
That would be my thought. As far as I can see 'POT' is not dysautonomia (almost the opposite) because it is a sign of a competent autonomic...
That sentence to me is unimpressive. The way to screen for these is already established. What exactly is being said here? I fear it is 'Why don't...
I wouldn't be so sure. The big problem with ME/CFS is that even the most mainstream biomedical inclined physicians specialising in it have a...
I would like to see how well controlled this study is. I am a bit leery of antibodies that react both to meninges and sciatica nerves being...
Yes, I doubt that the matrix proteins would show up although TGF binding protein variants might just. Regulators of interferon and TGF beta used...
Very much so. Brain itself has very personal matrix ingredients and does not rely on collagen and elastin in the way most tissues do. But meninges...
We have known for a long time that many EDS genotypes are defects in collagen-related genes - i.e. ECM. But the disease of elastin/fibrillin...
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