I think your hypothesis is good and I couldn't come up with anything better! I honestly don't know why taking it wouldn't work again, so can't...
I think that in theory I am in the ME1 subtype. I wore a continuous glucose monitor and got frequent hypoglycemias. I took a medication that...
I think I answered your first question in my recent reply to Hutan. In the model I refer to a hypovolemic type of POTs. I don't know what is the...
Well it could be either really, depending on your subtype and type of dysregulation. I am pretty sure with me it is cortisol, because when I took...
I would need to put some more thought into this, but the more obvious tests would be to test insulin response very regularly after an Oral Glucose...
Response to a deleted post. I can't give medical advice here but you could watch the video to find out more about the hypothetical ME3 subtype....
I am not sure if response to sugar and carbs is going to be the best way to differentiate subtypes. For example I have the ME1 subtype, had bad...
That is really interesting, but I am not sure why that happened!
I think ME1 and ME2 would feel worse from Methylphenidate because it increases extracellular norepinephrine, but ME1 may benefit from Guanfacine...
That's interesting! I follow Efthymios on twitter/X and he posts really interesting findings from his AI work. He posts a lot about liver...
I don't think you would move between subtypes, but you could move in stages through the illness. For example ME1 moving from overactive SNS to...
I also much feel better soon after VERY stressful situations. I think this is the high cortisol overriding the glucocorticoid receptor resistance,...
In the hypothesis, POTS is more a consequence of compensatory tachycardia due to excessive vasodilation. Yes I'm looking forward to the DecodeME...
The Sympathetic Nervous System is made up of noradrenergic neurons which release norepinephrine. This hypothesis suggests ME comprises three...
Hello I have been working on an ME Hypothesis for the last few years. It describes three types of noradrenergic neuron dysfunction, two of which...
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