@Lucibee Table 3 in the supplementary material to Collin and Crawley’s 2017 paper demonstrates exactly the effect you suggest, where a decrease...
It's a helpful guide, right? I've never tried amitriptyline, but I had bad side effects when put on low dose Effexor and then low dose Cymbalta...
PS When increasing night dose, I'd sometimes get a great night's sleep. Didn't last, though. It is supposed to improve the depth of your sleep....
I have surprised myself by being able to tolerate Neurontin/Gabapentin for no-longer-manageable all-over-body joint pain. I can't take...
Excellent! I'll take a paradigm shift, and I agree that that is what is needed. Thanks for being one of those aiming high. :thumbup:
So good to have people who know all of this! Yes, he was an author on the FINE trial paper. I do wonder if the negative trial dented their...
I found this really interesting, thanks for posting, @Sly Saint. Richard Bentall, the Clinical Psychologist, made criticisms of the overall...
These two quotes from Sharpe and White stood out to me in the huge report by Malcolm Hooper/Margaret Williams linked to above...
I agree. I think that there are many different parties that need convincing and different narratives convince different people. And while...
I think it’s important not to get sidetracked by the many points in this piece. The strength of the PACE crew's strategy is that they tell a...
If you look really, really closely at the treatment section of the SMC would-we-say-factsheet, you’ll see that medical care has a teeny tiny role:...
@Arnie Pye linked to this study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745581/ in a recent thread. Here's the abstract (below). It looks...
How about this one: [MEDIA] In case the tweet doesn't show, it's Carolyn Wilshire saying: "Keeping a copy of this awful tweet, which capitalises...
Thanks so much for putting this information in such an easy-to-grasp format, @Simon M , really impactful. Gobsmacking stuff. And this is the...
Thanks for that link, @Esther12 . My FINE folder is filling up. This playing with numbers until they tell the story you want makes me...
Thanks for that really clear explanation, @Valentijn . Wow. So that's 88 patients whose bimodal scores indicate abnormal fatigue being counted...
Thanks @dave30th . Hm. I think the fact that Alison Wearden, lead author of the FINE trial, is listed in the PACE trial 2011 paper as being on...
Again, you're right, and I've edited my post to point this out. Thanks! Just had a look at the PACE protocol paper, where they explain using a...
You're absolutely right, a typo, I've edited my post to correct this. Thanks!
I'm tortoising my way through your paper - congrats to all authors on having it accepted for publication. Building on @Sean ’s comment on...
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