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  1. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Another important point to discuss further I think.
    Post by: MSEsperanza, Apr 11, 2022 in forum: Trial design including bias, placebo effect
  2. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Thanks, Jonathan. Your expert testimony is already included in the submisson's references: "The problem of bias due to non-blinding of study...
    Post by: MSEsperanza, Apr 11, 2022 in forum: Trial design including bias, placebo effect
  3. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    This is not encouraging. Is this only a reaction you experienced when ME was involved, or was it a general attitude towards patients? if the...
    Post by: MSEsperanza, Apr 11, 2022 in forum: Trial design including bias, placebo effect
  4. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Not really able to comment at the moment but I think it's worthwhile to discuss further on these two points in particular. Another point I'd like...
    Post by: MSEsperanza, Apr 11, 2022 in forum: Trial design including bias, placebo effect
  5. MSEsperanza
    Post

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    In place of a screenshot: Right-click on the time stamp at top left of the news article & click 'save link'. Edit (had confounded top and...
    Post by: MSEsperanza, Apr 11, 2022 in forum: 2020 UK NICE ME/CFS Guideline
  6. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Thank you all for your comments on the IQWiG reply (posts starting at #180 ) Apologies for the confusion. I've tried to add some context and...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  7. MSEsperanza
    Post

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    This link still works for me:...
    Post by: MSEsperanza, Apr 10, 2022 in forum: 2020 UK NICE ME/CFS Guideline
  8. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Post above translated into English by deepl : From the IQWiG's draft of their General Methods paper: Section 3.4 'Nicht medikamentöse...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  9. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    From the submission to the IQWiG's draft of their General Methods Paper (in German) (*) (Each comment includes a proposed amendment.) Comments...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  10. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    This will take a while. Apologies. I will ask my health insurance if they could provide a personal assistant for my forum activity. Edit: ;)...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  11. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    Yes. Thanks @Hutan The comments were submitted by a private person to the IQWiG's draft of their General Methods paper. Each point of the quoted...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  12. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    To understand the background of the IQWiG's reply, I'll also post the second point of the comment which unfortunately might have facilitated...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  13. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    The German "bewerten" means both rate/ assess/ evaluate and 'conceive'. But I think the gist of comment (3) still applies (see post above this...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  14. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    I thought I'll provide the context of the IQWiG's reply to the said comments on their methods paper: The comments quoted in the other posts refer...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  15. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    But an interesting new example. Should we move this part of the discussion to the thread on interventions that manipulate how patients report...
    Post by: MSEsperanza, Apr 10, 2022 in forum: Trial design including bias, placebo effect
  16. MSEsperanza
    Post

    News from Germany

    This is from 1993.
    Post by: MSEsperanza, Apr 9, 2022 in forum: Regional news
  17. MSEsperanza
    Post

    News from Germany

    Very long article in a major German weekly newspaper. Warning: Contains insinuation of reaching out for possibilities of assisted suicide Long...
    Post by: MSEsperanza, Apr 9, 2022 in forum: Regional news
  18. MSEsperanza
    Post

    American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis, 1995, Felson et al.

    But why was there the need to develop a second system in the first place? What is the critique of the gold standard? Again, I think it would be...
    Post by: MSEsperanza, Apr 9, 2022 in forum: Other health news and research
  19. MSEsperanza
    Post

    Bias due to a lack of blinding: a discussion

    The Institute for Quality and Efficiency in Healthcare (IQWiG) in Germany is working on a report on the current state of knowledge on ME/CFS....
    Post by: MSEsperanza, Apr 9, 2022 in forum: Trial design including bias, placebo effect
  20. MSEsperanza
    Post

    American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis, 1995, Felson et al.

    If I remember properly, Graham's critique of how the SF-36 was used in the PACE trial addressed not only the issues with the altered recovery...
    Post by: MSEsperanza, Apr 9, 2022 in forum: Other health news and research
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