Is this really talking about LDN which is used for a rebound effect (as I understand it) of brief, mild inhibition of the receptor, or naltrexone...
Isn't heat-intolerance a common symptom of me/cfs for many? Of course it has many causes. I admit, although largely ignorant, I have always been...
I see Cort Johnson has written an article about nasal congestion, non allergic rhinitis and facial pain as it relates to me/cfs. The underlied...
I get it, that's why i'm saying, there was no particular stressor of any kind, I just gradual became ill. It wasn't a stressful period, I wasn't...
I have to say I'm always put-off by the default of the idea that me/cfs is 'stress of any kind unresolved'. I wasn't stressed emotionally or...
In case anyone else was curious. I believe they are going for 100 patients total, so probably less than 50% for part 1 and 15% done for part 2.
Did they mention how far along the intramural study was? I believe it started recruiting in 2016 and were fast approaching 2020.
Almost 2 years on since the 3 year grants were awarded.
It's interesting LDN is already used in me/cfs sometimes, I have often wanted to try campral - a drug that might be a palliative to pain and...
Reading that title made me feel gross.
One last thing. Isn't it strange that the SMC cohort had 4x the 'not-followed-up' of SMC + LP? (9 to 2). After all, it's included in the LP arm...
Quick note; study says mild/moderate me/cfs - I count 10 patients with sf-36-pfs of 25 or less - some were 15, one was 5 (wow!) and one was 10....
What was the gut bacteria he mentioned? Should be pretty easy to find if it's available and if it does anything. edit: doesn't seem commercially...
@Trish @Barry @Peter Trewhitt Thanks. It's great to have a place where we can have this kind of discussion and dig a little deeper as patients...
Thanks to @Trish most of what I’ve said looks fairly explainable. What it looks like now is the patients did swap cohorts, but were counted in...
Thank you, I can check the actual data. I didn't know it was released. I also did not know about Intention-to Treat and Pre-Protocol Analysis....
Imputed Participation Not knowing exact cohort participation creates problems w/ outcomes. One thing that stands out is cohort numbers for...
Sorry about the image size I hope that's not a problem.
Primary outcome tables and figures Crawley states 39 patients completed the SMC+LP. Figure 1 states that 39 patients received full SMC + LP....
I believe this represents the house visit stage. Patients filled out a consent to find out more information, then a researcher would come to their...
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