There are a bunch of bispecific mabs Blinatumomab (Blincyto), Emicizumab (Hemlibra), Amivantamab (Rybrevant), Teclistamab (Tecvayli),...
Isatuximab in the Treatment of Multiple Myeloma: A Review and Comparison With Daratumumab https://pmc.ncbi.nlm.nih.gov/articles/PMC9340383/
That’s a million dollar question. Maybe will hear something from Fluge next month. For cyclo, for the six year follow-up, a lot of the patients...
Immune system should come back—and hopefully normal-ish. I’m guessing that in multiple myeloma they need regular cycles with dara to keep cancer...
JE has brought up this one before (also known as Campath)—and there are some serious SEs. https://en.wikipedia.org/wiki/Alemtuzumab There is an...
I always thought the very low ESR finding was consistent, but contra this Stanford study...
And here https://www.s4me.info/threads/over-which-physiological-abnormalities-in-me-cfs-is-there-a-scientific-consensus-about.20900/
Thread here https://www.s4me.info/threads/biomedical-research-findings-in-me-cfs-that-were-replicated-by-multiple-groups-discussion-thread.16132/
Who said that Daratumumab is a high risk drug? It is pretty well tolerated, as is isatuximab. https://www.nature.com/articles/s41598-024-83014-1...
[MEDIA] @JanetDafoe I just talked to Ron and Rob about this. It’s another possible feedback loop that could count for the chronicity of the...
Also a subcutaneous formulation is underway. https://www.ajmc.com/view/subcutaneous-isatuximab-meets-primary-end-points-in-phase-3-study-for-mm
Seems like isatuximab is a “stronger” CD 38 drug than Daratumumab. Anyone have any guesses why Fluge’s group went with Dara over isatuximab?...
I did the same a couple of days ago—here is his reply. JB, I did not know about this, and I plan to join the Zoom of Max's talk. Because of...
The Ice Bucket Challenge worked. Why not try it again? The trend that dominated social media a decade ago — and raised millions for A.L.S....
Contractions in the knees? Is that an ME/CFS symptom? “ She said: "I can move everything now. Obviously I can talk, I can see. I can't walk and...
Twitter feed if that’s easier to read. [MEDIA] Highly speculative post: Autoimmune diseases have benefitted from a repurposing of modalities...
On how anti-aging therapies could piggyback on autoimmune treatment strategies in the same way the latter piggybacked on advances in cancer...
For scheduling a Zoom, if you are in St. Louis, probably some time between 9am and 2pm your time would work for most of the people on here (US,...
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