We'd need glial modulators. I don't think there's been a lot of R&D for those. Another reason for not administering drugs directly to the brain:...
I think this is a case of "the actual system is much more complicated than we're covering". If ME was as simple as inadequate SCFA production,...
Also, the responses to the questions may depend quite strongly on how the question is worded, and maybe even where in the questionnaire it is...
I was basing it on the 6+ temporary remissions I experienced, where I switched from full ME to full non-ME over the space of < 1 hr. That was...
I've never heard of that career before. What pops into mind is someone maintaining the cosmic computer that keeps the celestial bodies moving...
I'm trying to compare my fatigue(like) symptoms from ME with those from lack of sleep ... and I simply can't do that from memory. There must be...
This hypothesis fails my test for ME: if the symptoms are due to deposits, it doesn't fit the rapidity of switching from full ME to full non-ME...
My ME has never seemed to involve limited physical energy production. I might be very brainfogged, achy, and lethargic, but my legs would still...
"It's valid enough to look good in our study." I don't consider my memory of what I ate yesterday to be reliable. What I ate a month ago is pure...
My test for ME hypotheses is: "Does this fit with the rapid complete temporary remissions I experienced?" If the hypothesized mechanism doesn't...
ME is a vast experiment in treatments--each of us trying whatever catches our attention, plus all those foods, ingredients, and other possible...
That's one theory, but not one that I support. I don't believe that mitochondrial dysfunction is a core part of ME. ME might make me feel really...
Gimmick to get more followers? I'm clueless about social media, but I get the impression that some people live for gaining more followers.
No, it's "nuanced". I think I'll call all useless studies that.
That fits my definition of 'nuanced' (Does "nuanced" mean "adjust the studies and the goals <and study duration> until you get something that lets...
Sometimes it's valid to say "We don't know why x works, but it's an effective treatment, so prescribing it will improve the patient's life."...
I accepted the word "stress" as meaning stress on the muscles, rather than the psychological meaning of the word. That's the engineer in me, not...
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