I have thought that relative abundances of each fatty acid should affect membrane composition. Do the construction mechanisms in cells work from...
Whose brain are you offering for this taking apart? Also, human brains don't work very well when you take them apart, so you can't see the...
Are you more accustomed to using your arm muscles that way than you are using your leg muscles the way that causes PEM? For me, it seemed that it...
I must have missed those studies. What metabolic measures are abnormal? ATP production? Blood oxygen levels? Metabolic waste products?
I think muscles aren't directly involved in the mechanism of ME, but rather that signals from them can affect the ME mechanism. By this I mean...
I have unanticipated pain there too, but just one leg. It started after shoveling snow: I think it had to do with the repetitive sideways...
The problem with that is that the true believers will likely reject any trial that doesn't provide positive results, and it doesn't matter how...
Not proposing this as a strong hypothesis, but my ME provided evidence implying that my brain cells were overproducing quinolinic acid during my...
Has anyone ruled out neurological effects? Maybe something in brain or nerve function affects muscle function. Could it be some effect of immune...
It doesn't need to be rare, expensive, risky drugs. Two of my most effective treatments (cumin and iodine) were already in my kitchen. They...
I never noticed PEM from accumulated exertion. I always considered it to be triggered by specific actions (unaccustomed strain on muscles).
I'm optimistic about finding a treatment or cure, because I had temporary full remissions from three unrelated molecules: cuminaldehyde,...
Disorders that cause complete shutdown of a function don't mean that there can't be less severe disorders. My ME has responded to changes in...
However, the type of activity still matters, since the response to dosage varies with the activity. For me, less than a minute of window washing...
When I saw the title, I assumed a biological diagnostic test, meaning biomarker. That would be useful. Imagine if they tested the "chronic...
Maybe that could explain the variations in ME symptoms. If ME does affect mitochondrial activity, it might not affect all these diverse...
That's what I'm basing it on too. Abrupt temporary remissions are rare, but not extremely rare. It's always possible that rare cases represent a...
Some of the possible theories of immune memory causing ME fail my "Does this fit experiences of abrupt switching from full ME to full non-ME and...
An anecdotal report of "I think maybe it's kind of helping" isn't all that exciting. I was a bit disappointed by the method, because I was hoping...
Useful type of research. We need that sort of detail to figure out abnormalities. I wonder what percentage of papers citing this one will be...
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