Metabolomics of respiratory and other processes The authors go on to do metabolomics of respiratory and other processes related metabolites (3)....
Immunohistochemistry In their histology experiments (2) they show some stains where it looks like there is greater IDO-2 expression in PBMCs...
Overall there are some possibly interesting bits in the paper but they don't all hang together as a cogent story in my opinion. There is no single...
I think it's a long shot but I sent her an email to inquire.
Great news! I'm guessing maybe that means 14-15k DNA samples actually being received with an ~80% sample return rate. Fingers crossed we'll get...
this is getting a bit off topic but I'm curious if you think there is a sensible tissue to look at/biopsy in general for ME. Or with our current...
My partner thinks it might not be unreasonable to not see things like this if the phenotype is not that strong, as the coverage can be quite low...
You might already know this - One of the proteins in this talk PD-1 was associated with a recent nobel prize along with CTLA-4. These genes are...
Good point! Just looking back at their scRNA-seq preprint and they do report they see some differences (measured by gene ontology enrichment...
The logic kind of seems fair enough, although I wonder if comparing the whole curve might in someway dilute the signal from whichever source of...
They are using Renyi entropy which is sort of a generalised measure of diversity which includes many different measures of diversity within it....
Things like this also make it sound like the technique has potential: Would be cool to see it done on GWAS data from other diseases where much...
They outline the methods in a bit more detail in the ME paper and I think I have a slightly better handle on how they're doing the statistics. It...
Just catching up on the threads on the ME paper precision life and @Simon M's blog post - really interesting. They find 14 possible genes in the...
It's fundamentally a bad faith argument though isn't it. He's using an argument about the condition having a bad name to somehow justify the leap...
It's a very small experiment with 4 controls and 4 'chronic fatigue' patients with no mention of diagnosis criteria or age and sex matching etc....
I seem to remember it being because Ron's student R Esfandyarpour - the first author on the nanoneedle paper - was starting his own lab and needed...
I dîd the lightning process about a decade ago and you have to read a book about it first and do an interview. I was just in a relapse so health...
They use 200mM NaCl in the nanoneedle paper which is why I mentioned that number above. You would think that would be enough to really hurt, as I...
Might depend on the cell type but I think cells have salt concentrations of about 150mM and so like to sit in an isotonic buffer of about 150mM...
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