Moved post I was looking for a good thread to put in some interesting recent progress I've made on IBS, and this one will have to do. I had been...
An interesting matrix to explore with a survey might be I have POTS symptoms, am alcohol intolerant I have POTS symptoms, am NOT alcohol...
I would like to reiterate my original post: DOMS and PEM are different. DOMS is adaptive. PEM is pathological. DOMS is local. PEM is systemic. One...
Near the beginning of my me/cfs adventure, I was in what was essentially remission. I'd been sick really acutely for about 4 months, then suddenly...
There are a couple of athletic phenomena that could share some similarities with ME/CFS. Over trainign syndrome is one: My understanding of this...
Salubrinal came to our attention via the Hwang study on WASF3. That study showed endoplasmic reticulum stress was causing WASF3 production and the...
I've encountered references to matrix metalloproteinaise a few times recently. https://en.wikipedia.org/wiki/MMP9 Its functions relate to the...
SHe replies: Glad to hear from you and thank you for your interest in the work (not a lot of it in this space, as you perhaps already know)....
My read of their other papers suggests the distinction is not that it is 3D printed, but that other researchers are using 2d layers of muscle...
There's a 2023 paper here that talks about the history and process behind "3D muscle models". Muscle-on-a-chip devices: a new era for in vitro...
Is this a PEM model? we need so desperately to have a benchtop model in this disease. Working on people is so slow, expensive and variable. I...
Good to have this hypothesis formalised and published. I'm a little skeptical of how widespread this could be as an etiology of mecfs but perhaps...
Small sample but they do also blend two other cohorts in and look for commonalities. This is not game-changing research or cure-finding research...
I'm sharing this because it's an example of a metabolic issue with a barrier component. And involves STAT singalling, which I know the stanford...
IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis Peng Zhang 1 , Junlai Liu 1 , Allen Lee 1 ,...
I think sit / lie flat is an interesting dichotomy but legs up is a very important intermediate. I once had an office job where I wore a suit and...
I'm always interested in any hypothesis with an adrenergic connection. beta blockers have been very useful for me, as has midodrine, an alpha...
Berlin Cures will reveal the results of the BC007 Phase II trial in November at a Long Covid conference....
Excellent group of test subjects. I hope they have continued to follow up with them and seen how their health goes beyond 60 days. From 1170...
You can see some level of self-selection in my response to the email from Baker institute: > thanks for the email. I'm probably going to hold off...
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